Literature DB >> 7810590

Association of apolipoprotein E allele epsilon 4 with late-onset sporadic Alzheimer's disease.

G Lucotte1, S Visvikis, B Leininger-Müler, F David, S Berriche, S Réveilleau, R Couderc, M C Babron, D Aguillon, G Siest.   

Abstract

Apolipoprotein E, type epsilon 4 allele (ApoE epsilon 4), is associated with late-onset sporadic Alzheimer's disease (AD) in French patients. The association is highly significant (0.45 AD versus 0.12 controls for epsilon 4 allele frequencies). These data support the involvement of ApoE epsilon 4 allele as a very important risk factor for the clinical expression of AD.

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Year:  1994        PMID： 7810590     DOI： 10.1002/ajmg.1320540319

Source DB:  PubMed          Journal:  Am J Med Genet        ISSN： 0148-7299


  7 in total

Review 1.  Interaction of apolipoprotein E epsilon 4 with other genetic and non-genetic risk factors in late onset Alzheimer disease: problems facing the investigator.

Authors:  R Katzman; D Kang; R Thomas
Journal:  Neurochem Res       Date:  1998-03       Impact factor: 3.996

2.  Inter- and intra-chromosomal modulators of the APOE ɛ2 and ɛ4 effects on the Alzheimer's disease risk.

Authors:  Alireza Nazarian; Ian Philipp; Irina Culminskaya; Liang He; Alexander M Kulminski
Journal:  Geroscience       Date:  2022-07-09       Impact factor: 7.713

Review 3.  Can infections cause Alzheimer's disease?

Authors:  Francis Mawanda; Robert Wallace
Journal:  Epidemiol Rev       Date:  2013-01-24       Impact factor: 6.222

4.  An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.

Authors:  Todd L Edwards; Margaret Pericak-Vance; Johnny R Gilbert; Jonathan L Haines; Eden R Martin; Marylyn D Ritchie
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2009-07-05       Impact factor: 3.568

5.  Cardiovascular damage in Alzheimer disease: autopsy findings from the Bryan ADRC.

Authors:  Elizabeth H Corder; John F Ervin; Evelyn Lockhart; Mari H Szymanski; Donald E Schmechel; Christine M Hulette
Journal:  J Biomed Biotechnol       Date:  2005-06-30

Review 6.  The Role of Butyrylcholinesterase and Iron in the Regulation of Cholinergic Network and Cognitive Dysfunction in Alzheimer's Disease Pathogenesis.

Authors:  Jacek Jasiecki; Monika Targońska; Bartosz Wasąg
Journal:  Int J Mol Sci       Date:  2021-02-18       Impact factor: 5.923

Review 7.  Dysregulated Ca2+ Homeostasis as a Central Theme in Neurodegeneration: Lessons from Alzheimer's Disease and Wolfram Syndrome.

Authors:  Manon Callens; Jens Loncke; Geert Bultynck
Journal:  Cells       Date:  2022-06-18       Impact factor: 7.666
  7 in total

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