Literature DB >> 7809207

Cytotoxic and antiparasitic activity from Annona senegalensis seeds.

S Sahpaz1, C Bories, P M Loiseau, D Cortès, R Hocquemiller, A Laurens, A Cavé.   

Abstract

Several extracts of Annona senegalensis (Annonaceae) seeds were tested for antiparasitic activity against Leishmania major, Leishmania donovani, Trypanosoma brucei brucei, and for cytotoxic activity against KB and VERO cell lines. Fractionation of seeds extracts was mainly guided by means of a biocidal assay against Artemia salina nauplii. The biological activities resulted from extract-isolated acetogenins.

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Year:  1994        PMID： 7809207     DOI： 10.1055/s-2006-959566

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  3 in total

1.  Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors.

Authors:  Gordon J Florence; Andrew L Fraser; Eoin R Gould; Elizabeth F B King; Stefanie K Menzies; Joanne C Morris; Lindsay B Tulloch; Terry K Smith
Journal:  ChemMedChem       Date:  2014-08-21       Impact factor: 3.466

2.  Anthelminthic activity of acetone extract and fractions of Vernonia amygdalina against Haemonchus contortus eggs and larvae.

Authors:  Isaiah Oluwafemi Ademola; J N Eloff
Journal:  Trop Anim Health Prod       Date:  2010-11-19       Impact factor: 1.559

3.  Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors.

Authors:  Gordon J Florence; Andrew L Fraser; Eoin R Gould; Elizabeth F King; Stefanie K Menzies; Joanne C Morris; Marie I Thomson; Lindsay B Tulloch; Marija K Zacharova; Terry K Smith
Journal:  ChemMedChem       Date:  2016-06-10       Impact factor: 3.466
  3 in total

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