| Literature DB >> 7807130 |
N Bouaicha1, P Amade, D Puel, C Roussakis.
Abstract
From a CH2Cl2 extract of the Mediterranean sponge Anchinoe paupertas were isolated and characterized zarzissine [2], a new 4,5-guanidino-pyridazine compound and the known p-hydroxybenzaldehyde [1]. The structure of zarzissine [2] was elucidated by spectroscopic methods, including the application of a number of 2D nmr techniques. Biological activities of compounds 1 and 2 were also determined, with zarzissine exhibiting cytotoxicity against three human and murine tumor cell lines.Entities:
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Year: 1994 PMID： 7807130 DOI： 10.1021/np50112a019
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050