Literature DB >> 7806439

An association between sputum eosinophilia and carcinoma of the lung: a study of 549 patients.

P Wright1, P Kelly, J Yazbeck, L Clancy, T Healy.   

Abstract

A prospective 11 year study of sputum cytology in 5,475 patients with respiratory diseases other than asthma or Loeffler's syndrome showed that carcinoma of the lung was the commonest single condition associated with a sputum eosinophilia: it occurred in 68 (12.4%) of the 549 patients with pulmonary carcinoma. While clearly not a diagnostic finding, sputum eosinophilia should stimulate, in appropriate cases, a further search for carcinoma. The cause or causes of the eosinophilia are not known at present but the body's reaction to malignancy is a topical subject of study worldwide.

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Year:  1994        PMID: 7806439     DOI: 10.1007/bf02967091

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  13 in total

Review 1.  The immunobiology of eosinophils.

Authors:  P F Weller
Journal:  N Engl J Med       Date:  1991-04-18       Impact factor: 91.245

2.  Bronchial cancer and hypereosinophilia.

Authors:  P Remacle; J Bruart; C Henneghien
Journal:  Eur Respir J       Date:  1988-02       Impact factor: 16.671

3.  Letter: Eosinophilia in bronchogenic carcinoma.

Authors:  A L Dellon; R B Hume; P B Chretien
Journal:  N Engl J Med       Date:  1974-07-25       Impact factor: 91.245

4.  Letter: Eosinophilia in bronchogenic carcinoma.

Authors:  T M Healy
Journal:  N Engl J Med       Date:  1974-10-10       Impact factor: 91.245

5.  Tumor-associated eosinophilotactic factor.

Authors:  S I Wasserman; E J Goetzl; L Ellman; K F Austen
Journal:  N Engl J Med       Date:  1974-02-21       Impact factor: 91.245

6.  Constitutive expression of the granulocyte-macrophage colony-stimulating factor gene in human solid tumors.

Authors:  H Mano; J Nishida; K Usuki; Y Maru; Y Kobayashi; H Hirai; T Okabe; A Urabe; F Takaku
Journal:  Jpn J Cancer Res       Date:  1987-10

7.  Production of granulocyte-macrophage colony-stimulating factor in two patients with lung cancer, leukocytosis, and eosinophilia.

Authors:  C L Sawyers; D W Golde; S Quan; S D Nimer
Journal:  Cancer       Date:  1992-03-15       Impact factor: 6.860

Review 8.  Allergic bronchopulmonary aspergillosis. Model of bronchopulmonary disease with defined serologic, radiologic, pathologic and clinical findings from asthma to fatal destructive lung disease.

Authors:  P A Greenberger; R Patterson
Journal:  Chest       Date:  1987-06       Impact factor: 9.410

9.  Local responses in primary and secondary human lung cancers. I. Patterns of cellular (eosinophils and macrophages) and extracellular (acid mucopolysaccharide) reactions.

Authors:  E Müller; E Kolb
Journal:  Br J Cancer       Date:  1979-09       Impact factor: 7.640

10.  Pulmonary eosinophilia.

Authors:  D M Geddes
Journal:  J R Coll Physicians Lond       Date:  1986-04
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