Literature DB >> 7805695

In vitro antibacterial activity of sucralfate.

D Bergmans1, M Bonten, C Gaillard, F van Tiel, S van der Geest, E Stobberingh.   

Abstract

The effect of sucralfate (12.5 mg/ml) on the growth of Escherichia coli (ATCC 25922), Enterococcus faecalis (ATCC 29212) and two isolates of Pseudomonas aeruginosa (ATCC 27853 and a multi-resistant clinical isolate) was studied in vitro at pH values of 3.0, 4.5, 6.0 and 7.4. A bacteriostatic effect of sucralfate was demonstrated for Pseudomonas aeruginosa at a pH of 6.0 and 7.4 and for Escherichia coli and Enterococcus faecalis at a pH of 6.0. The bacteriostatic effect was most pronounced at high pH values. Sucralfate had no bactericidal effect on the bacteria tested at the concentration used.

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Year:  1994        PMID： 7805695     DOI： 10.1007/bf01971318

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN： 0934-9723            Impact factor:   3.267


  10 in total

1.  A surface plating technic for determining bacterial population of milk.

Authors:  W L MALLMANN; S A BROITMAN
Journal:  Am J Public Health Nations Health       Date:  1956-08

2.  Stress ulcer prophylaxis and ventilation pneumonia: prevention by antibacterial cytoprotective agents?

Authors:  F Daschner; I Kappstein; I Engels; K Reuschenbach; J Pfisterer; N Krieg; W Vogel
Journal:  Infect Control Hosp Epidemiol       Date:  1988-02       Impact factor: 3.254

3.  Antibacterial activity of sucralfate and bismuth subsalicylate in simulated gastric fluid.

Authors:  I Kappstein; I Engels
Journal:  Eur J Clin Microbiol       Date:  1987-04       Impact factor: 3.267

4.  Gastric exocrine "failure" in critically ill patients: incidence and associated features.

Authors:  V A Stannard; A Hutchinson; D L Morris; A Byrne
Journal:  Br Med J (Clin Res Ed)       Date:  1988-01-16

5.  Effects of electrolytes in carbohydrate beverages on gastric emptying and secretion.

Authors:  N J Rehrer; E J Beckers; F Brouns; W H Saris; F Ten Hoor
Journal:  Med Sci Sports Exerc       Date:  1993-01       Impact factor: 5.411

6.  Antibacterial activity of sucralfate against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa in batch and continuous culture.

Authors:  A P West; S Abdul; M J Sherratt; T J Inglis
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1993-11       Impact factor: 3.267

7.  Risk of acute stress bleeding and nosocomial pneumonia in ventilated intensive care unit patients: sucralfate versus antacids.

Authors:  M Tryba
Journal:  Am J Med       Date:  1987-09-28       Impact factor: 4.965

8.  Antibacterial activity of sucralfate in human gastric juice.

Authors:  M Tryba; F Mantey-Stiers
Journal:  Am J Med       Date:  1987-09-28       Impact factor: 4.965

9.  A comparison of the frequency of stress ulceration and secondary pneumonia in sucralfate- or ranitidine-treated intensive care unit patients.

Authors:  J M Eddleston; A Vohra; P Scott; J A Tooth; R C Pearson; R F McCloy; A K Morton; B H Doran
Journal:  Crit Care Med       Date:  1991-12       Impact factor: 7.598

10.  Nosocomial pneumonia in intubated patients given sucralfate as compared with antacids or histamine type 2 blockers. The role of gastric colonization.

Authors:  M R Driks; D E Craven; B R Celli; M Manning; R A Burke; G M Garvin; L M Kunches; H W Farber; S A Wedel; W R McCabe
Journal:  N Engl J Med       Date:  1987-11-26       Impact factor: 91.245
  10 in total
  2 in total

1.  Influence of intravenously administered ciprofloxacin on aerobic intestinal microflora and fecal drug levels when administered simultaneously with sucralfate.

Authors:  W A Krueger; G Ruckdeschel; K Unertl
Journal:  Antimicrob Agents Chemother       Date:  1997-08       Impact factor: 5.191

2.  Efficacy of topical sucralfate vERSUs silver sulfadiazine in the management of burns: A 1-year randomized controlled trial.

Authors:  A S Godhi; P Ram; R Powar
Journal:  J West Afr Coll Surg       Date:  2017 Jan-Mar
  2 in total

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