Human papillomavirus in condyloma acuminata and other benign lesions of the female genital tract.

PCR was used to detect (HPV) in condyloma acuminata (CA), pseudocondyloma whose cause is unclear, and the other benign lesions in female genital tract. The results showed that HPV prevalence rate in CA was 98.2%, type 6 was in 11 was 85.7%, and that in pseudocondyloma, cervical polyp, cervical erosion and chronic vaginitis was 40.4%, 76.2%, 77.3% and 16.0%, respectively. Even in normal vaginal tissue, there existed HPV subclinical infection. HPV prevalence rate in swabs from patient's underwears and normal vaginal tissues was 73.6% and 54.0% respectively. The investigation of estrogen receptor (ER) in CA tissue carried out by immunohistochemical method found that positive ER was achieved in most of CA, and few of normal vulvar tissues was found. This result indicated that the occurrence of CA is probably related to estrogen.