| Literature DB >> 7805134 |
H Susaki1, K Suzuki, M Ikeda, H Yamada, H K Watanabe.
Abstract
Arginine-vasopressin (AVP) derivatives modified at the glutamine side chain amide with carbohydrate via an alkylene spacer (1a--d) were synthesized from new glycosylated glutamine derivatives (3a--d) by solid-phase synthesis. Glycoconjugates of AVP modified at the C-terminal amide (2a--d) were also synthesized from vasopressionic acid. All of them exhibited antidiuretic activity.Entities:
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Year: 1994 PMID： 7805134 DOI： 10.1248/cpb.42.2090
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645