Literature DB >> 7804993

Skin cancer in African Americans.

R M Halder1, S Bridgeman-Shah.   

Abstract

Skin cancer is the most common type of malignancy in the United States. Incidence within the African American population remains relatively low, but data is limited for this racial group, making accurate determination of incidence and mortality difficult. Factors implicated as causative in the pathogenesis of cutaneous malignancy in African Americans include, but are by no means limited to, sunlight, albinism, burn scars, X-rays, preexisting pigmented lesions, chronic inflammation, and chronic discoid lupus erythematosus. Anatomic distribution of lesions may be similar to that seen in whites for basal cell carcinoma but not for other skin cancers. For squamous cell carcinoma, melanoma, and cutaneous T-cell lymphoma, African Americans do not as well in terms of mortality as do whites. This difference probably is due either to the fact that African Americans have more advanced stages of disease at diagnosis than do whites or, in some cases, because the course of the disease is more aggressive in African Americans for reasons yet unknown. There is a need for heightened awareness of skin cancer in African Americans by patients and physicians. Emphasis should be on education and early diagnosis with the primary goal in mind being the reduction of incidence of and mortality due to skin cancer in African Americans. In addition, because of environmental factors, African Americans will be exposed to more solar ultraviolet radiation in the future. Strategies should be developed for public education to keep this exposure to low levels in this racial group.

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Mesh:

Year:  1995        PMID: 7804993     DOI: 10.1002/1097-0142(19950115)75:2+<667::aid-cncr2820751409>3.0.co;2-i

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  49 in total

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3.  Skin cancer prevention: a time for action.

Authors:  S A Everett; G A Colditz
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5.  Genome-wide transcriptome analysis of human epidermal melanocytes.

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7.  Treatment and outcomes of melanoma in acral location in Korean patients.

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Review 8.  Skin cancer in skin of color.

Authors:  Porcia T Bradford
Journal:  Dermatol Nurs       Date:  2009 Jul-Aug

9.  Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin.

Authors:  Seiji Takeuchi; Wengeng Zhang; Kazumasa Wakamatsu; Shosuke Ito; Vincent J Hearing; Kenneth H Kraemer; Douglas E Brash
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10.  Incidence of nonmelanoma skin cancer in a cohort of patients with vitiligo.

Authors:  Camile L Hexsel; Melody J Eide; Christine C Johnson; Richard Krajenta; Gordon Jacobsen; Iltefat Hamzavi; Henry W Lim
Journal:  J Am Acad Dermatol       Date:  2009-04-17       Impact factor: 11.527

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