BACKGROUND: We consider how well the psychosocial and clinical factors found to predict a chronic course for depressive episodes in the community, held for female psychiatric patients. METHOD: A consecutive series of depressed patients, aged 18 to 60, treated as in-patients, out-patients or day-patients at psychiatric departments of two London hospitals, were interviewed initially and at follow-up two years later. RESULTS: Indices of childhood adversity and current interpersonal difficulties predicted episodes taking a chronic course (of more than 12 months' duration). Half of the episodes associated with one or the other factor were chronic, compared with 22% of those with neither. The patients were at higher risk than the community series (75% v. 34%) and this explains their much greater rate of chronicity. There was also some evidence that social support reduced risk. Clinical features and the presence of a personality disorder were unrelated to chronicity. CONCLUSIONS: Similar psychosocial factors are important for predicting chronicity in both community and patient series.
BACKGROUND: We consider how well the psychosocial and clinical factors found to predict a chronic course for depressive episodes in the community, held for female psychiatricpatients. METHOD: A consecutive series of depressedpatients, aged 18 to 60, treated as in-patients, out-patients or day-patients at psychiatric departments of two London hospitals, were interviewed initially and at follow-up two years later. RESULTS: Indices of childhood adversity and current interpersonal difficulties predicted episodes taking a chronic course (of more than 12 months' duration). Half of the episodes associated with one or the other factor were chronic, compared with 22% of those with neither. The patients were at higher risk than the community series (75% v. 34%) and this explains their much greater rate of chronicity. There was also some evidence that social support reduced risk. Clinical features and the presence of a personality disorder were unrelated to chronicity. CONCLUSIONS: Similar psychosocial factors are important for predicting chronicity in both community and patient series.
Authors: Wael Shamseddeen; Joan Rosenbaum Asarnow; Gregory Clarke; Benedetto Vitiello; Karen Dineen Wagner; Boris Birmaher; Martin B Keller; Graham Emslie; Satish Iyengar; Neal D Ryan; James T McCracken; Giovanna Porta; Taryn Mayes; David A Brent Journal: J Am Acad Child Adolesc Psychiatry Date: 2011-01-14 Impact factor: 8.829
Authors: Katie A McLaughlin; Jennifer Greif Green; Michael J Gruber; Nancy A Sampson; Alan M Zaslavsky; Ronald C Kessler Journal: Arch Gen Psychiatry Date: 2010-02
Authors: Helen L Fisher; Sarah Cohen-Woods; Georgina M Hosang; Ania Korszun; Mike Owen; Nick Craddock; Ian W Craig; Anne E Farmer; Peter McGuffin; Rudolf Uher Journal: J Affect Disord Date: 2012-07-25 Impact factor: 4.839
Authors: Cindy-Lee Dennis; Paula Ravitz; Sophie Grigoriadis; Melissa Jovellanos; Ellen Hodnett; Lori Ross; John Zupancic Journal: Trials Date: 2012-04-19 Impact factor: 2.279