Literature DB >> 7803366

Phenelzine reduces plasma vitamin B6.

D E Malcolm1, P H Yu, R C Bowen, C O'Donovan, J Hawkes, M Hussein.   

Abstract

Plasma levels of the active form of vitamin B6 (pyridoxal phosphate) in 19 patients taking phenelzine were found to be reduced on the average to approximately 54% of the value in a control group. There was no correlation of pyridoxal phosphate level with phenelzine daily dosage over the range of 30 mg to 90 mg. No symptoms of vitamin B6 deficiency peripheral neuropathy were found.

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Year:  1994        PMID: 7803366      PMCID: PMC1188621     

Source DB:  PubMed          Journal:  J Psychiatry Neurosci        ISSN: 1180-4882            Impact factor:   6.186


  7 in total

1.  Pyridoxine-deficiency neuropathy due to hydralazine.

Authors:  N H Raskin; R A Fishman
Journal:  N Engl J Med       Date:  1965-11-25       Impact factor: 91.245

2.  Determination of plasma pyridoxal 5'-phosphate by an enzymatic-high-performance liquid chromatographic procedure.

Authors:  P H Yu
Journal:  Anal Biochem       Date:  1989-09       Impact factor: 3.365

Review 3.  Drug--vitamin B6 interaction.

Authors:  H N Bhagavan; M Brin
Journal:  Curr Concepts Nutr       Date:  1983

Review 4.  Drug-pyridoxal phosphate interactions.

Authors:  M Ebadi; C F Gessert; A Al-Sayegh
Journal:  Q Rev Drug Metab Drug Interact       Date:  1982

5.  Pyridoxine deficiency and peripheral neuropathy associated with long-term phenelzine therapy.

Authors:  C A Heller; P A Friedman
Journal:  Am J Med       Date:  1983-11       Impact factor: 4.965

6.  Phenelzine-induced pyridoxine deficiency.

Authors:  J W Stewart; W Harrison; F Quitkin; M R Liebowitz
Journal:  J Clin Psychopharmacol       Date:  1984-08       Impact factor: 3.153

7.  Phenelzine treatment of panic disorder: lack of effect on pyridoxal phosphate levels.

Authors:  R B Lydiard; M T Laraia; E F Howell; M D Fossey; R D Reynolds; J C Ballenger
Journal:  J Clin Psychopharmacol       Date:  1989-12       Impact factor: 3.153

  7 in total
  1 in total

1.  Tailored Pyridoxal Probes Unravel Novel Cofactor-Dependent Targets and Antibiotic Hits in Critical Bacterial Pathogens.

Authors:  Martin Pfanzelt; Thomas E Maher; Ramona M Absmeier; Markus Schwarz; Stephan A Sieber
Journal:  Angew Chem Int Ed Engl       Date:  2022-04-12       Impact factor: 16.823

  1 in total

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