Literature DB >> 7802676

Molecular cloning and sequence analysis of a human 372-kDA protein localized in the Golgi complex.

M Sohda1, Y Misumi, T Fujiwara, M Nishioka, Y Ikehara.   

Abstract

Autoantibodies from a patient with chronic rheumatoid arthritis recognized an antigen localized in the Golgi complex of various cells from different tissues and species. The autoantibodies were used as a probe for screening human QGP-1 cDNA library, resulting in identification of a 10.3-kb cDNA. The cDNA insert contained an open reading frame which encodes a 3225-residue protein with a calculated mass of 372 kDa. The predicted protein was found to have no NH2-terminal signal sequence but a single hydrophobic domain at the COOH terminus. These results indicate that the 372-kDa antigen is cytoplasmically disposed and anchored to the Golgi membrane by the COOH-terminal hydrophobic domain.

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Year:  1994        PMID： 7802676     DOI： 10.1006/bbrc.1994.2821

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  9 in total

1.  Amino acid substitutions of coiled-coil protein Tpr abrogate anchorage to the nuclear pore complex but not parallel, in-register homodimerization.

Authors:  M E Hase; N V Kuznetsov; V C Cordes
Journal:  Mol Biol Cell       Date:  2001-08       Impact factor: 4.138

2.  Intracellular cleavage of glycosylphosphatidylinositol by phospholipase D induces activation of protein kinase Calpha.

Authors:  H Tsujioka; N Takami; Y Misumi; Y Ikehara
Journal:  Biochem J       Date:  1999-09-01       Impact factor: 3.857

3.  ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites.

Authors:  Jun Sasaki; Kumiko Ishikawa; Minetaro Arita; Koki Taniguchi
Journal:  EMBO J       Date:  2011-11-29       Impact factor: 11.598

4.  Proteomic identification of S-nitrosylated Golgi proteins: new insights into endothelial cell regulation by eNOS-derived NO.

Authors:  Panjamaporn Sangwung; Todd M Greco; Yanzhuang Wang; Harry Ischiropoulos; William C Sessa; Yasuko Iwakiri
Journal:  PLoS One       Date:  2012-02-21       Impact factor: 3.240

5.  GMAP-210, A cis-Golgi network-associated protein, is a minus end microtubule-binding protein.

Authors:  C Infante; F Ramos-Morales; C Fedriani; M Bornens; R M Rios
Journal:  J Cell Biol       Date:  1999-04-05       Impact factor: 10.539

6.  Peri-Golgi vesicles contain retrograde but not anterograde proteins consistent with the cisternal progression model of intra-Golgi transport.

Authors:  J A Martinez-Menárguez; R Prekeris; V M Oorschot; R Scheller; J W Slot; H J Geuze; J Klumperman
Journal:  J Cell Biol       Date:  2001-12-17       Impact factor: 10.539

7.  Characterization of a cis-Golgi matrix protein, GM130.

Authors:  N Nakamura; C Rabouille; R Watson; T Nilsson; N Hui; P Slusarewicz; T E Kreis; G Warren
Journal:  J Cell Biol       Date:  1995-12       Impact factor: 10.539

8.  Expression of AR-V7 (Androgen Receptor Variant 7) Protein in Granular Cytoplasmic Structures Is an Independent Prognostic Factor in Prostate Cancer Patients.

Authors:  Paul König; Markus Eckstein; Rudolf Jung; Amer Abdulrahman; Juan Guzman; Katrin Weigelt; Ginette Serrero; Jun Hayashi; Carol Geppert; Robert Stöhr; Arndt Hartmann; Bernd Wullich; Sven Wach; Helge Taubert; Verena Lieb
Journal:  Cancers (Basel)       Date:  2020-09-16       Impact factor: 6.639

9.  Fragmentation of Golgi complex and Golgi autoantigens during apoptosis and necrosis.

Authors:  Kazuhisa Nozawa; Carlos A Casiano; John C Hamel; Christine Molinaro; Marvin J Fritzler; Edward K L Chan
Journal:  Arthritis Res       Date:  2002-06-11
  9 in total

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