[Type II Charcot-Marie-Tooth and dopa-sensitive Parkinson disease].

The occurrence of a dopa-sensitive parkinsonian syndrome 25 years after a neuropathy suggestive of Charcot-Marie-Tooth disease type II raised the possibility of a relationship between these two diseases. Apart from Machado-Joseph-Azorean disease, an association of this kind seems to be exceptional and it can not be excluded that it was fortuitous. However, the recent description of 7 familial and sporadic cases of a syndrome characterized by a peripheral neuropathy, familial in 5 of the 7 cases, followed, a few years later, by a dopa-sensitive parkinsonian syndrome, makes it possible to consider that this association might have a common genetic origin.