Literature DB >> 779941

Prophylactic antibiotic therapy and heart valve replacement.

T W Austin, J C Coles, R Finley, B Schieven.   

Abstract

Patients undergoing cardiac bypass for heart valve replacement maintained adequate blood concentrations of cloxacillin throughout the duration of bypass, provided their initial blood concentration was in the therapeutic range. Blood levels related to the time between the last preoperative dose of antibiotic and operation. Maximal values were achieved if an intraoperative bolus of drug was given.

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Year:  1976        PMID: 779941

Source DB:  PubMed          Journal:  Can J Surg        ISSN: 0008-428X            Impact factor:   2.089


  1 in total

1.  Concentrations of fusidic acid, cloxacillin, and cefamandole in sera and atrial appendages of patients undergoing cardiac surgery.

Authors:  M G Bergeron; D Desaulniers; C Lessard; M Lemieux; J P Després; J Métras; G Raymond; G Brochu
Journal:  Antimicrob Agents Chemother       Date:  1985-06       Impact factor: 5.191

  1 in total

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