| Literature DB >> 7798955 |
Abstract
Two new benzo[c]phenanthridine alkaloids, 6-methyldihydrochelerythrine [1] and 6-methylnorchelerythrine [2], together with 23 known compounds, were isolated from the root bark of Zanthoxylum simulans. Structures were elucidated by spectral analysis. Among them, the pyranoquinoline alkaloids, zanthosimuline [3], and huajiaosimuline [4], exhibited cytotoxic activity. In addition, compound 4 showed significant antiplatelet aggregation activity and induced terminal differentiation with cultured HL-60 cells.Entities:
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Year: 1994 PMID： 7798955 DOI： 10.1021/np50111a003
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050