Literature DB >> 7798003

Bleeding after tonsillectomy in severe von Willebrand's disease.

G H Alusi1, W E Grant, C A Lee, K J Pasi, M P Stearns.   

Abstract

A case is reported of a HIV-positive patient with severe von Willebrand's disease describing the bleeding complications during and after tonsillectomy. This patient underwent surgery for asymmetrical tonsillar hypertrophy. The tonsils were spontaneously haemorrhaging and there therefore was a suspicion of neoplasia. Despite close cooperation between the ENT Department and the Haemophilia Centre, involving per-operative Factor VIII monitoring and replacement, the patient suffered both protracted primary and secondary haemorrhages. We report this as a cautionary tale as our previous experience with mild to moderate haemophilia has been uncomplicated, but on this occasion there was massive haemorrhage. We feel that tonsillectomy should not be undertaken in a patient with a severe bleeding disorder without an absolute indicate.

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Year:  1995        PMID: 7798003     DOI: 10.1017/s0022215100130373

Source DB:  PubMed          Journal:  J Laryngol Otol        ISSN: 0022-2151            Impact factor:   1.469


  1 in total

1.  Prophylactic efficacy and pharmacokinetically guided dosing of a von Willebrand factor/factor VIII concentrate in adults and children with von Willebrand's disease undergoing elective surgery: a pooled and comparative analysis of data from USA and European Union clinical trials.

Authors:  Pier Mannuccio Mannucci; Paul Alexander Kyrle; Sam Schulman; Jorge Di Paola; Reinhard Schneppenheim; Joan Cox Gill
Journal:  Blood Transfus       Date:  2013-04-17       Impact factor: 3.443

  1 in total

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