Literature DB >> 7796052

Dioxides of bicyclic thiadiazines: a new family of smooth muscle relaxants.

A Castro1, A Martínez, I Cardelús, J Llenas.   

Abstract

The synthesis of dioxides of bicyclic thiadiazine related to diazoxide has been achieved. In a preliminary test, some of these compounds show smooth muscle relaxation similar to that obtained with the reference standard diazoxide.

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Year:  1995        PMID: 7796052     DOI: 10.1016/0968-0896(95)00012-6

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  2 in total

1.  Lipophilicity screening of novel drug-like compounds and comparison to clog P.

Authors:  Dujuan Lu; Peter Chambers; Peter Wipf; Xiang-Qun Xie; Danielle Englert; Stephen Weber
Journal:  J Chromatogr A       Date:  2012-08-01       Impact factor: 4.759

2.  Synthesis and Selective Functionalization of Thiadiazine 1,1-Dioxides with Efficacy in a Model of Huntington's Disease.

Authors:  Leila Terrab; Christopher J Rosenker; Lisa Johnstone; Linh K Ngo; Li Zhang; Nathaniel F Ware; Bettina Miller; Andrea Z Topacio; Sara Sannino; Jeffrey L Brodsky; Peter Wipf
Journal:  ACS Med Chem Lett       Date:  2020-02-20       Impact factor: 4.345

  2 in total

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