Literature DB >> 7795796

Determination of chlorhexidine in saliva using high-performance liquid chromatography.

T Pesonen1, J Holmalahti, J Pohjola.   

Abstract

A reversed-phase high-performance liquid chromatographic method for the determination of chlorhexidine in saliva is reported. The method developed includes a simple and short sample preparation with a one-step extraction procedure and a short total chromatographic run time of 5 min. In a preliminary pharmacokinetic study with a healthy volunteer the chlorhexidine concentration found in saliva after 12 h was 0.8 microgram/ml.

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Year:  1995        PMID: 7795796     DOI: 10.1016/0378-4347(94)00514-6

Source DB:  PubMed          Journal:  J Chromatogr B Biomed Appl        ISSN: 1572-6495


  2 in total

1.  Effects of low-concentrated chlorhexidine on growth of Streptococcus sobrinus and primary human gingival fibroblasts.

Authors:  S Dogan; H Günay; G Leyhausen; W Geurtsen
Journal:  Clin Oral Investig       Date:  2003-08-22       Impact factor: 3.573

2.  Preparation, in vitro characterization and preliminary in vivo evaluation of buccal polymeric films containing chlorhexidine.

Authors:  Claudia Juliano; Massimo Cossu; Paola Pigozzi; Giovanna Rassu; Paolo Giunchedi
Journal:  AAPS PharmSciTech       Date:  2008-11-19       Impact factor: 3.246

  2 in total

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