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Literature DB >> 7793954

A serine (threonine) protein kinase confers fungicide resistance in the phytopathogenic fungus Ustilago maydis.

A B Orth¹, M Rzhetskaya, E J Pell, M Tien.

Abstract

A mutant of Ustilago maydis (VR43) with single-gene resistance to the dicarboximide fungicide vinclozolin was previously isolated and characterized. A genomic library was constructed, and an 8.7-kb resistance-conferring fragment was isolated by sib selection. Sequencing this fragment, we identified an 1,218-bp open reading frame, which, if disrupted by deletion, no longer confers resistance. Analyses of the data in GenBank demonstrated a high degree of homology between the product of the 1,218-bp open reading frame, referred to as the adr-1 gene, and Ser (Thr) protein kinases.

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Year: 1995 PMID： 7793954 PMCID： PMC167505 DOI： 10.1128/aem.61.6.2341-2345.1995

Source DB: PubMed Journal: Appl Environ Microbiol ISSN： 0099-2240 Impact factor: 4.792

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