Literature DB >> 7791740

In vivo effect of vitamin E on serum and tissue glycoprotein levels in perchloroethylene induced cytotoxicity.

A S Ebrahim1, R Gopalakrishnan, A Murugesan, D Sakthisekaran.   

Abstract

The antioxidant efficacy of vitamin E on Perchloroethylene (PER) induced cytotoxicity has been studied in rats. Feeding PER to rats for 42 days using sesame oil as vehicle alters total protein and protein bound carbohydrate components in liver and kidney of experimental animals. Supplementation of vitamin E prevented the changes observed in total protein and protein bound carbohydrate components of PER administered rats. Histopathological studies also show the effectiveness of vitamin E on PER administered rats in protecting the cellular architecture of liver and kidney from PER induced cytotoxicity.

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Year:  1995        PMID： 7791740     DOI： 10.1007/bf00926735

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  22 in total

1.  Serum polysaccharide levels in rats bearing the Walker 256 tumor.

Authors:  M R SHETLAR; C P ERWIN; M R EVERETT
Journal:  Cancer Res       Date:  1950-07       Impact factor: 12.701

2.  Serum sialic acid in rats bearing Yoshida ascites sarcoma.

Authors:  V S Rao; M Sirsi
Journal:  Indian J Biochem       Date:  1970-09

3.  Influence of trace metals on serum total sialic acids and perchloric acid--soluble proteins and sialic acids in mice.

Authors:  A B Patel; H Venkatakrishna-Bhatt
Journal:  J Appl Toxicol       Date:  1989-02       Impact factor: 3.446

4.  Sialic acid and neuraminidase activity in rat kidneys 6 months after uninephrectomy.

Authors:  D Allalouf; U Gafter; T Malachi; J Hirsh; J Levi; H Levinsky
Journal:  Biochem Med Metab Biol       Date:  1988-04

5.  Vinyl chloride and trichloroethylene: comparison of alkylating effects of metabolites and induction of preneoplastic enzyme deficiencies in rat liver.

Authors:  R J Laib; G Stöckle; H M Bolt; W Kunz
Journal:  J Cancer Res Clin Oncol       Date:  1979-06-08       Impact factor: 4.553

6.  Lipid composition and fatty acid pattern of the gerbil brain after exposure to perchloroethylene.

Authors:  T Kyrklund; P Kjellstrand; K G Haglid
Journal:  Arch Toxicol       Date:  1987-07       Impact factor: 5.153

7.  Delineation of the role of metabolism in the hepatotoxicity of trichloroethylene and perchloroethylene: a dose-effect study.

Authors:  J A Buben; E J O'Flaherty
Journal:  Toxicol Appl Pharmacol       Date:  1985-03-30       Impact factor: 4.219

8.  Biochemical, histological, and ultrastructural changes in rat and mouse liver following the administration of trichloroethylene: possible relevance to species differences in hepatocarcinogenicity.

Authors:  C R Elcombe; M S Rose; I S Pratt
Journal:  Toxicol Appl Pharmacol       Date:  1985-07       Impact factor: 4.219

9.  Perchloroethylene-induced rat kidney tumors: an investigation of the mechanisms involved and their relevance to humans.

Authors:  T Green; J Odum; J A Nash; J R Foster
Journal:  Toxicol Appl Pharmacol       Date:  1990-03-15       Impact factor: 4.219

10.  Irreversible binding of chlorinated ethylenes to macromolecules.

Authors:  H M Bolt; J G Filser
Journal:  Environ Health Perspect       Date:  1977-12       Impact factor: 9.031
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  2 in total

1.  Effect of vitamin E on protein bound carbhohydrate complexes in radiation treated oral squamous cell carcinoma patients.

Authors:  S Chitra; C S Shyamala Devi
Journal:  Indian J Clin Biochem       Date:  2008-03-06

2.  Studies on the neuroprotective role of Piper longum in C6 glioma induced rats.

Authors:  Umadevi Subramanian; Sharmila Poongavanam; A J Vanisree
Journal:  Invest New Drugs       Date:  2010-10       Impact factor: 3.850
  2 in total

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