| Literature DB >> 779156 |
N Wedderburn, J L Turk, M S Hutt.
Abstract
Chronic malarial infection was established in Balb/c mice by following Plasmodium berghei yoelii with P.b. berghei infection. It was found that the IgG plaque-forming cell response to sheep erythrocytes was depressed for at least six months. A preliminary investigation of the histological changes in the spleen and liver is described. The possibility that chronically infected mice could serve as a model for the tropical splenomegaly syndrome is discussed.Entities:
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Year: 1975 PMID： 779156 DOI： 10.1016/0035-9203(75)90099-1
Source DB: PubMed Journal: Trans R Soc Trop Med Hyg ISSN： 0035-9203 Impact factor: 2.184