| Literature DB >> 7791035 |
M Henczi1, J Nagy, D F Weaver.
Abstract
Octanol-water partition coefficients have been measured and calculated for eight clinically relevant anticonvulsants. For some compounds, these are the first experimentally available log P values. For the remainder of the molecules, new values have been suggested. The utility of the micro shake-flask experimental method and the ALOGP calculational method in determining anticonvulsant log P values has been demonstrated.Entities:
Mesh：
Substances：
Year: 1995 PMID： 7791035 DOI： 10.1111/j.2042-7158.1995.tb05807.x
Source DB: PubMed Journal: J Pharm Pharmacol ISSN： 0022-3573 Impact factor: 3.765