Literature DB >> 7790033

Antibody-induced modulation of CD26 surface expression.

T Mattern1, C Reich, M Duchrow, S Ansorge, A J Ulmer, H D Flad.   

Abstract

The ability of different anti-CD26 monoclonal antibodies to modulate the expression of CD26 on human T lymphocytes was investigated. By means of a new non-radioactive method using fluorescein isothiocyanate (FITC)-labelled and unlabelled anti-CD26 monoclonal antibodies and flow cytometry, we measured the internalization and re-expression of CD26 on freshly isolated resting human T lymphocytes. The modulation of CD26 surface expression takes place in primarily CD26+ as well as in CD26- T lymphocytes, indicating the presence of an intracellular CD26 pool. In fact, with two different anti-CD26 monoclonal antibodies (Ta1 and M5) intracellular CD26 was detected out of which newly expressed CD26 might have originated. This intracellular CD26 pool appears to be maintained by continuous translation of CD26 mRNA.

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Year:  1995        PMID： 7790033      PMCID： PMC1415157     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  28 in total

1.  Localization and turnover of dipeptidylpeptidase IV in the domains of rat liver plasma membrane.

Authors:  R Büchsel; W Kreisel; B Fringes; C Hanski; W Reutter; W Gerok
Journal:  Eur J Cell Biol       Date:  1986-03       Impact factor: 4.492

2.  Heterogeneous turnover of terminal and core sugars within the carbohydrate chain of dipeptidylaminopeptidase IV isolated from rat liver plasma membrane.

Authors:  B A Volk; W Kreisel; E Köttgen; W Gerok; W Reutter
Journal:  FEBS Lett       Date:  1983-10-31       Impact factor: 4.124

3.  OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties.

Authors:  J P Van Wauwe; J R De Mey; J G Goossens
Journal:  J Immunol       Date:  1980-06       Impact factor: 5.422

4.  Antibody-induced receptor loss. Different fates for asialoglycoproteins and the asialoglycoprotein receptor in HepG2 cells.

Authors:  A L Schwartz; A Ciechanover; S Merritt; A Turkewitz
Journal:  J Biol Chem       Date:  1986-11-15       Impact factor: 5.157

5.  Different half-lives of the carbohydrate and protein moieties of a 110,000-dalton glycoprotein isolated from plasma membranes of rat liver.

Authors:  W Kreisel; B A Volk; R Büchsel; W Reutter
Journal:  Proc Natl Acad Sci U S A       Date:  1980-04       Impact factor: 11.205

6.  Influence of avidity and idiotope recognition on the modulation of surface immunoglobulin on malignant human B cells by rat monoclonal anti-idiotype antibodies.

Authors:  M Campbell; M Bieber; R Levy; N N Teng
Journal:  J Immunol       Date:  1986-04-15       Impact factor: 5.422

7.  Function of dipeptidyl peptidase IV (CD26, Tp103) in transfected human T cells.

Authors:  M Hegen; D Camerini; B Fleischer
Journal:  Cell Immunol       Date:  1993-02       Impact factor: 4.868

8.  Antigenic modulation. Loss of TL antigen from cells exposed to TL antibody. Study of the phenomenon in vitro.

Authors:  L J Old; E Stockert; E A Boyse; J H Kim
Journal:  J Exp Med       Date:  1968-03-01       Impact factor: 14.307

9.  Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells.

Authors:  C R Hopkins; I S Trowbridge
Journal:  J Cell Biol       Date:  1983-08       Impact factor: 10.539

10.  Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen).

Authors:  T Hara; S M Fu; J A Hansen
Journal:  J Exp Med       Date:  1985-06-01       Impact factor: 14.307
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  8 in total

1.  Degranulation of human cytotoxic lymphocytes is a major source of proteolytically active soluble CD26/DPP4.

Authors:  Marcus Lettau; Michelle Dietz; Sarah Vollmers; Fred Armbrust; Christian Peters; Thi Mai Dang; Guranda Chitadze; Dieter Kabelitz; Ottmar Janssen
Journal:  Cell Mol Life Sci       Date:  2019-07-12       Impact factor: 9.261

Review 2.  Dipeptidyl peptidase-4 and kidney fibrosis in diabetes.

Authors:  Sen Shi; Daisuke Koya; Keizo Kanasaki
Journal:  Fibrogenesis Tissue Repair       Date:  2016-02-13

Review 3.  Intra- and Extracellular Effector Vesicles From Human T And NK Cells: Same-Same, but Different?

Authors:  Marcus Lettau; Ottmar Janssen
Journal:  Front Immunol       Date:  2021-12-23       Impact factor: 7.561

4.  Distinctive CD26 Expression on CD4 T-Cell Subsets.

Authors:  Oscar J Cordero; Carlos Rafael-Vidal; Rubén Varela-Calviño; Cristina Calviño-Sampedro; Beatriz Malvar-Fernández; Samuel García; Juan E Viñuela; José M Pego-Reigosa
Journal:  Biomolecules       Date:  2021-10-02

Review 5.  The Serine Protease CD26/DPP4 in Non-Transformed and Malignant T Cells.

Authors:  Guranda Chitadze; Ulrike Wehkamp; Ottmar Janssen; Monika Brüggemann; Marcus Lettau
Journal:  Cancers (Basel)       Date:  2021-11-26       Impact factor: 6.639

Review 6.  DPP4 in Diabetes.

Authors:  Diana Röhrborn; Nina Wronkowitz; Juergen Eckel
Journal:  Front Immunol       Date:  2015-07-27       Impact factor: 7.561

Review 7.  Pharmacology, physiology, and mechanisms of action of dipeptidyl peptidase-4 inhibitors.

Authors:  Erin E Mulvihill; Daniel J Drucker
Journal:  Endocr Rev       Date:  2014-09-12       Impact factor: 19.871

Review 8.  CD26 and Asthma: a Comprehensive Review.

Authors:  Juan J Nieto-Fontarigo; Francisco J González-Barcala; Esther San José; Pilar Arias; Montserrat Nogueira; Francisco J Salgado
Journal:  Clin Rev Allergy Immunol       Date:  2019-04       Impact factor: 8.667
  8 in total

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