Literature DB >> 7786668

Reversal of haemochromatotic cardiomyopathy in beta thalassaemia by chelation therapy.

A Politi1, M Sticca, M Galli.   

Abstract

Haemochromatotic cardiomyopathy is the main cause of morbidity and mortality in patients with beta thalassaemia major. Once congestive heart failure develops most patients die in a few months. Congestive heart failure was reversed and echocardiographic findings were restored to normal in a 24 year old woman with beta thalassaemia who resumed treatment with chelation therapy (desferrioxamine).

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Year:  1995        PMID: 7786668      PMCID: PMC483870          DOI: 10.1136/hrt.73.5.486

Source DB:  PubMed          Journal:  Br Heart J        ISSN: 0007-0769


  6 in total

1.  Prolonged survival in patients with beta-thalassemia major treated with deferoxamine.

Authors:  K H Ehlers; P J Giardina; M L Lesser; M A Engle; M W Hilgartner
Journal:  J Pediatr       Date:  1991-04       Impact factor: 4.406

2.  Restrictive diastolic abnormalities identified by Doppler echocardiography in patients with thalassemia major.

Authors:  P Spirito; G Lupi; C Melevendi; C Vecchio
Journal:  Circulation       Date:  1990-07       Impact factor: 29.690

3.  Successful reversal by chelation therapy of congestive cardiomyopathy due to iron overload.

Authors:  P S Rahko; R Salerni; B F Uretsky
Journal:  J Am Coll Cardiol       Date:  1986-08       Impact factor: 24.094

4.  Cardiopulmonary assessment in beta-thalassemia major.

Authors:  D Grisaru; E A Rachmilewitz; M Mosseri; M Gotsman; J S Lafair; E Okon; A Goldfarb; Y Hasin
Journal:  Chest       Date:  1990-11       Impact factor: 9.410

5.  High incidence of cardiomyopathy in beta-thalassaemia patients receiving regular transfusion and iron chelation: reversal by intensified chelation.

Authors:  M A Aldouri; B Wonke; A V Hoffbrand; D M Flynn; S E Ward; J E Agnew; A J Hilson
Journal:  Acta Haematol       Date:  1990       Impact factor: 2.195

6.  [Severe cardiomyopathy in a woman with intermediate beta-thalassemia. Regression of cardiac failure with desferrioxamine].

Authors:  L Mancuso; M A Iacona; S Marchi; P Rigano; E Geraci
Journal:  G Ital Cardiol       Date:  1985-09
  6 in total
  1 in total

1.  d-Propranolol protects against oxidative stress and progressive cardiac dysfunction in iron overloaded rats.

Authors:  Jay H Kramer; Christopher F Spurney; Micaela Iantorno; Constantine Tziros; Joanna J Chmielinska; I Tong Mak; William B Weglicki
Journal:  Can J Physiol Pharmacol       Date:  2012-08-22       Impact factor: 2.273

  1 in total

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