Literature DB >> 7786475

Diterpenoids from Isodon eriocalyx var. laxiflora.

H D Sun1, Z W Lin, F D Niu, P Q Shen, L T Pan, L Z Lin, G A Cordell.   

Abstract

Three new, seco-ent-kaurane diterpenoids, laxiflorins A, B and C, together with four known diterpenoids eriocalyxin B, oriodonin, and maeocrystals A and B, were isolated from the leaves of Isodon eriocalyx var. laxiflora. Their structures were assigned by a combination of one- and two-dimensional NMR techniques and computer modeling calculations. Laxiflorin C displayed weak cytotoxic activity.

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Year:  1995        PMID: 7786475     DOI: 10.1016/0031-9422(94)00815-b

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  6 in total

1.  Eriocalyxin B Inhibits STAT3 Signaling by Covalently Targeting STAT3 and Blocking Phosphorylation and Activation of STAT3.

Authors:  Xiaokui Yu; Li He; Peng Cao; Qiang Yu
Journal:  PLoS One       Date:  2015-05-26       Impact factor: 3.240

Review 2.  Bioactive Natural Spirolactone-Type 6,7-seco-ent-Kaurane Diterpenoids and Synthetic Derivatives.

Authors:  Haonan Li; Runwei Jiao; Jiahui Mu; Shengtao Xu; Xu Li; Xianhua Wang; Zhanlin Li; Jinyi Xu; Huiming Hua; Dahong Li
Journal:  Molecules       Date:  2018-11-08       Impact factor: 4.411

Review 3.  Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response.

Authors:  Milad Ashrafizadeh; Mahshid Deldar Abad Paskeh; Sepideh Mirzaei; Mohammad Hossein Gholami; Ali Zarrabi; Farid Hashemi; Kiavash Hushmandi; Mehrdad Hashemi; Noushin Nabavi; Francesco Crea; Jun Ren; Daniel J Klionsky; Alan Prem Kumar; Yuzhuo Wang
Journal:  J Exp Clin Cancer Res       Date:  2022-03-22

Review 4.  Solubility and Bioavailability Enhancement of Oridonin: A Review.

Authors:  Yuanyuan Zhang; Shaohua Wang; Mengmeng Dai; Jijuan Nai; Liqiao Zhu; Huagang Sheng
Journal:  Molecules       Date:  2020-01-14       Impact factor: 4.411

5.  Eriocalyxin B Induces Apoptosis and Autophagy Involving Akt/Mammalian Target of Rapamycin (mTOR) Pathway in Prostate Cancer Cells.

Authors:  Ziqiang Yu; Yang Chen; Chaozhao Liang
Journal:  Med Sci Monit       Date:  2019-11-12

6.  Preventive and therapeutic effect of intraportal oridonin on BALb/c nude mice hemispleen model of colon cancer liver metastasis.

Authors:  Yu-Shen Yang; Dan Wen; Xue-Feng Zhao
Journal:  Transl Cancer Res       Date:  2021-03       Impact factor: 1.241

  6 in total

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