| Literature DB >> 778604 |
J D Young, J W Gorman, J A Gorman, R M Bock.
Abstract
The small basic oligopeptide antibiotic, netropsin, can be successfully employed as an effective counterselecting agent in Saccharomyces cerevisiae. The use of the drug results in approximately a 35-fold enrichment of auxotrophic mutants in a mutagenized culture of yeast. The experimental procedure is quite simple and less time consuming than other presently used methods for indirect mutant selection in yeast.Entities:
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Year: 1976 PMID： 778604 DOI： 10.1016/0027-5107(76)90204-9
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433