| Literature DB >> 778588 |
Abstract
By using rifampicin to increase the rate of beta and beta' synthesis in a heterodiploid strain of E. coli carrying the mutation rifpr (Km7), which codes for a rifampicin sensitive RNA polymerase to which the drug binds weakly, and the dominant mutation rifRD, which codes for a rifampicin resistant RNA polymerase, the concentration of these subunits in the cell was increased 1.6 fold. Measurements made after removal of rifampicin from the cells showed that the excess beta and beta' subunits did not reduce the rate of their own synthesis below normal.Entities:
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Year: 1976 PMID: 778588 DOI: 10.1007/bf00269598
Source DB: PubMed Journal: Mol Gen Genet ISSN: 0026-8925