PURPOSE/ METHODS: We conducted this study to determine if the herpesviruses are possible etiologic agents in Posner-Schlossman syndrome. We aspirated aqueous humor samples from patients during acute attacks of the syndrome. Ten normal aqueous humor specimens from patients undergoing cataract surgery were used as controls. DNA was extracted and subjected to polymerase chain reaction amplification and Southern blot hybridization. RESULTS/ CONCLUSION: All three specimens were positive for amplified genomic fragments of herpes simplex virus and negative for varicella-zoster virus and cytomegalovirus. Ten normal aqueous specimens were negative for all three. Herpes simplex virus may play a role in the origin of Posner-Schlossman syndrome.
PURPOSE/ METHODS: We conducted this study to determine if the herpesviruses are possible etiologic agents in Posner-Schlossman syndrome. We aspirated aqueous humor samples from patients during acute attacks of the syndrome. Ten normal aqueous humor specimens from patients undergoing cataract surgery were used as controls. DNA was extracted and subjected to polymerase chain reaction amplification and Southern blot hybridization. RESULTS/ CONCLUSION: All three specimens were positive for amplified genomic fragments of herpes simplex virus and negative for varicella-zoster virus and cytomegalovirus. Ten normal aqueous specimens were negative for all three. Herpes simplex virus may play a role in the origin of Posner-Schlossman syndrome.
Authors: Vaibhav Tiwari; Christian Clement; Perry M Scanlan; Devanand Kowlessur; Beatrice Y J T Yue; Deepak Shukla Journal: J Virol Date: 2005-10 Impact factor: 5.103
Authors: M Pahlitzsch; N Torun; J Gonnermann; A K B Maier; U Pleyer; E Bertelmann; A Joussen; M K J Klamann Journal: Eye (Lond) Date: 2015-07-03 Impact factor: 3.775
Authors: N Koizumi; K Nishida; W Adachi; M Tei; Y Honma; A Dota; C Sotozono; N Yokoi; S Yamamoto; S Kinoshita Journal: Br J Ophthalmol Date: 1999-08 Impact factor: 4.638