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Literature DB >> 7784330

Transfollicular drug delivery.

A C Lauer¹, L M Lieb, C Ramachandran, G L Flynn, N D Weiner.

Abstract

The hair follicle, hair shaft, and sebaceous gland collectively form what is recognized as the pilosebaceous unit. This complex, three-dimensional structure within the skin possesses a unique biochemistry, metabolism and immunology. Recent studies have focused on the hair follicle as a potential pathway for both localized and systemic drug delivery. Greater understanding of the structure and function of the hair follicle may facilitate rational design of drug formulations to target follicular delivery. Targeted drug delivery may enhance current therapeutic approaches to treating diseases of follicular origin. Presented here is a review of follicular drug delivery and a discussion of the feasibility of the pilosebaceous unit as a target site.

Mesh：

Year: 1995 PMID： 7784330 DOI： 10.1023/a:1016250422596

Source DB: PubMed Journal: Pharm Res ISSN： 0724-8741 Impact factor: 4.200

37 in total

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Journal: J Invest Dermatol Date: 1967-01 Impact factor: 8.551

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Journal: J Invest Dermatol Date: 1993-07 Impact factor: 8.551

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Authors: G Plewig; C Luderschmidt
Journal: J Invest Dermatol Date: 1977-04 Impact factor: 8.551

10 in total

1. Characterization of a new tissue-engineered human skin equivalent with hair.

Authors: M Michel; N L'Heureux; R Pouliot; W Xu; F A Auger; L Germain
Journal: In Vitro Cell Dev Biol Anim Date: 1999-06 Impact factor: 2.416

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Authors: Ylva Y Grams; Joke A Bouwstra
Journal: Pharm Res Date: 2002-03 Impact factor: 4.200

3. Effect of direction (epidermis-to-dermis and dermis-to-epidermis) on the permeation of several chemical compounds through full-thickness skin and stripped skin.

Authors: Takeshi Oshizaka; Hiroaki Todo; Kenji Sugibayashi
Journal: Pharm Res Date: 2012-05-24 Impact factor: 4.200

4. Skin healing and collagen changes of rats after fractional erbium:yttrium aluminum garnet laser: observation by reflectance confocal microscopy with confirmed histological evidence.

Authors: Jing Yang; Sha Wang; Liyun Dong; Xiangjie An; Yan Li; Jun Li; Yating Tu; Juan Tao
Journal: Lasers Med Sci Date: 2016-06-08 Impact factor: 3.161

5. Low intensity ultrasound as a probe to elucidate the relative follicular contribution to total transdermal absorption.

Authors: V M Meidan; M Docker; A D Walmsley; W J Irwin
Journal: Pharm Res Date: 1998-01 Impact factor: 4.200

6. Determining the Effect of pH on the Partitioning of Neutral, Cationic and Anionic Chemicals to Artificial Sebum: New Physicochemical Insight and QSPR Model.

Authors: Senpei Yang; Lingyi Li; Tao Chen; Lujia Han; Guoping Lian
Journal: Pharm Res Date: 2018-05-14 Impact factor: 4.200

7. An integrated pharmacokinetic and imaging evaluation of vehicle effects on solute human epidermal flux and, retention characteristics.

Authors: G Winckle; Y G Anissimov; S E Cross; G Wise; M S Roberts
Journal: Pharm Res Date: 2007-09-22 Impact factor: 4.200

8. Significant suppression of radiation dermatitis in breast cancer patients using a topically applied adrenergic vasoconstrictor.

Authors: James F Cleary; Bethany M Anderson; Jens C Eickhoff; Deepak Khuntia; William E Fahl
Journal: Radiat Oncol Date: 2017-12-22 Impact factor: 3.481

9. Effect of Enhancers on in vitro and in vivo Skin Permeation and Deposition of S-Methyl-_L-Methionine.

Authors: Ki Taek Kim; Ji Su Kim; Min-Hwan Kim; Ju-Hwan Park; Jae-Young Lee; WooIn Lee; Kyung Kuk Min; Min Gyu Song; Choon-Young Choi; Won-Serk Kim; Hee Kyung Oh; Dae-Duk Kim
Journal: Biomol Ther (Seoul) Date: 2017-07-01 Impact factor: 4.634

Review 10. Iontophoresis of Biological Macromolecular Drugs.

Authors: Mahadi Hasan; Anowara Khatun; Kentaro Kogure
Journal: Pharmaceutics Date: 2022-02-26 Impact factor: 6.321

10 in total