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Literature DB >> 7784218

8-Methoxypsoralen photoinduced plasmid-chromosome recombination in Saccharomyces cerevisiae using a centromeric vector.

L B Meira¹, J A Henriques, N Magaña-Schwencke.

Abstract

The characterization of a new system to study the induction of plasmid-chromosome recombination is described. Single-stranded and double-stranded centromeric vectors bearing 8-methoxypsoralen photoinduced lesions were used to transform a wild-type yeast strain bearing the leu2-3,112 marker. Using the SSCP methodology and DNA sequencing, it was demonstrated that repair of the lesions in plasmid DNA was mainly due to conversion of the chromosomal allele to the plasmid DNA.

Entities: Chemical Gene Species

Mesh：

Substances：
Methoxsalen

Year: 1995 PMID： 7784218 PMCID： PMC306905 DOI： 10.1093/nar/23.9.1614

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

24 in total

1. Mutation spectrum following transfection of ultraviolet-irradiated single-stranded or double-stranded shuttle vector DNA into monkey cells.

Authors: C Madzak; A Sarasin
Journal: J Mol Biol Date: 1991-04-20 Impact factor: 5.469

2. Defect in excision repair alters the mutational specificity of PUVA treatment in the lacI gene of Escherichia coli.

Authors: F Yatagai; M J Horsfall; B W Glickman
Journal: J Mol Biol Date: 1987-04-20 Impact factor: 5.469

Review 3. The reaction of the psoralens with deoxyribonucleic acid.

Authors: J E Hearst; S T Isaacs; D Kanne; H Rapoport; K Straub
Journal: Q Rev Biophys Date: 1984-02 Impact factor: 5.318

4. Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations.

Authors: A Aguilera; H L Klein
Journal: Genetics Date: 1988-08 Impact factor: 4.562

5. Analysis of single-stranded DNA stability and damage-induced strand loss in mammalian cells using SV40-based shuttle vectors.

Authors: C Madzak; C F Menck; J Armier; A Sarasin
Journal: J Mol Biol Date: 1989-02-05 Impact factor: 5.469

6. Mutagenic and recombinogenic action of DNA monoadducts photoinduced by the bifunctional furocoumarin 8-methoxypsoralen in yeast (Saccharomyces cerevisiae).

Authors: D Averbeck; S Averbeck; E Cundari
Journal: Photochem Photobiol Date: 1987-03 Impact factor: 3.421

7. Induction of multiple plasmid recombination in Saccharomyces cerevisiae by psoralen reaction and double strand breaks.

Authors: W A Saffran; E D Smith; S K Chan
Journal: Nucleic Acids Res Date: 1991-10-25 Impact factor: 16.971

8-Methoxypsoralen photoinduced plasmid-chromosome recombination in Saccharomyces cerevisiae using a centromeric vector.

1. Mutation spectrum following transfection of ultraviolet-irradiated single-stranded or double-stranded shuttle vector DNA into monkey cells.

2. Defect in excision repair alters the mutational specificity of PUVA treatment in the lacI gene of Escherichia coli.

Review 3. The reaction of the psoralens with deoxyribonucleic acid.

4. Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations.

5. Analysis of single-stranded DNA stability and damage-induced strand loss in mammalian cells using SV40-based shuttle vectors.

6. Mutagenic and recombinogenic action of DNA monoadducts photoinduced by the bifunctional furocoumarin 8-methoxypsoralen in yeast (Saccharomyces cerevisiae).

7. Induction of multiple plasmid recombination in Saccharomyces cerevisiae by psoralen reaction and double strand breaks.

8. Transformation of Saccharomyces cerevisiae with UV-irradiated single-stranded plasmid.

9. DNA interstrand cross-links promote chromosomal integration of a selected gene in human cells.

10. Studies on transformation of Escherichia coli with plasmids.

1. Processing of targeted psoralen cross-links in Xenopus oocytes.

2. Genome Sequencing and Comparative Analysis of Saccharomyces cerevisiae Strains of the Peterhof Genetic Collection.