Literature DB >> 7783114

Design and syntheses of potent and selective dipeptide inhibitors of Candida albicans myristoyl-CoA:protein N-myristoyltransferase.

B Devadas1, M E Zupec, S K Freeman, D L Brown, S Nagarajan, J A Sikorski, C A McWherter, D P Getman, J I Gordon.   

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Year:  1995        PMID： 7783114     DOI： 10.1021/jm00011a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  9 in total

1.  Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.

Authors:  Hong Jiang; Xiaoyu Zhang; Xiao Chen; Pornpun Aramsangtienchai; Zhen Tong; Hening Lin
Journal:  Chem Rev       Date:  2018-01-02       Impact factor: 60.622

2.  Protein myristoylation in health and disease.

Authors:  Megan H Wright; William P Heal; David J Mann; Edward W Tate
Journal:  J Chem Biol       Date:  2009-11-07

3.  Profiling of myristoylation in Toxoplasma gondii reveals an N-myristoylated protein important for host cell penetration.

Authors:  Malgorzata Broncel; Caia Dominicus; Luis Vigetti; Stephanie D Nofal; Edward J Bartlett; Bastien Touquet; Alex Hunt; Bethan A Wallbank; Stefania Federico; Stephen Matthews; Joanna C Young; Edward W Tate; Isabelle Tardieux; Moritz Treeck
Journal:  Elife       Date:  2020-07-03       Impact factor: 8.140

4.  Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors.

Authors:  Stephen Brand; Laura A T Cleghorn; Stuart P McElroy; David A Robinson; Victoria C Smith; Irene Hallyburton; Justin R Harrison; Neil R Norcross; Daniel Spinks; Tracy Bayliss; Suzanne Norval; Laste Stojanovski; Leah S Torrie; Julie A Frearson; Ruth Brenk; Alan H Fairlamb; Michael A J Ferguson; Kevin D Read; Paul G Wyatt; Ian H Gilbert
Journal:  J Med Chem       Date:  2011-12-07       Impact factor: 7.446

Review 5.  Drug discovery for neglected diseases: molecular target-based and phenotypic approaches.

Authors:  Ian H Gilbert
Journal:  J Med Chem       Date:  2013-09-09       Impact factor: 7.446

6.  Peptidomimetic inhibitors of N-myristoyltransferase from human malaria and leishmaniasis parasites.

Authors:  Tayo O Olaleye; James A Brannigan; Shirley M Roberts; Robin J Leatherbarrow; Anthony J Wilkinson; Edward W Tate
Journal:  Org Biomol Chem       Date:  2014-09-18       Impact factor: 3.876

7.  QSAR Study of N-Myristoyltransferase Inhibitors of Antimalarial Agents.

Authors:  Letícia Santos-Garcia; Marco Antônio de Mecenas Filho; Kamil Musilek; Kamil Kuca; Teodorico Castro Ramalho; Elaine Fontes Ferreira da Cunha
Journal:  Molecules       Date:  2018-09-13       Impact factor: 4.411

8.  A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors.

Authors:  Justin R Harrison; Stephen Brand; Victoria Smith; David A Robinson; Stephen Thompson; Alasdair Smith; Kenneth Davies; Ngai Mok; Leah S Torrie; Iain Collie; Irene Hallyburton; Suzanne Norval; Frederick R C Simeons; Laste Stojanovski; Julie A Frearson; Ruth Brenk; Paul G Wyatt; Ian H Gilbert; Kevin D Read
Journal:  J Med Chem       Date:  2018-09-12       Impact factor: 7.446

9.  Structure-guided optimization of quinoline inhibitors of Plasmodium N-myristoyltransferase.

Authors:  Victor Goncalves; James A Brannigan; Alice Laporte; Andrew S Bell; Shirley M Roberts; Anthony J Wilkinson; Robin J Leatherbarrow; Edward W Tate
Journal:  Medchemcomm       Date:  2016-11-11       Impact factor: 3.597
  9 in total

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