Literature DB >> 7779254

The human immunoglobulin VH repertoire.

G P Cook1, I M Tomlinson.   

Abstract

A complete map of the human immunoglobulin VH locus on chromosome 14 has recently been constructed. The locus is 1100kb in length and contains 51 functional VH segments interspersed amongst a similar number of pseudogenes. Here, Graham Cook and Ian Tomlinson review the organization of the locus, its polymorphism and the repertoire it encodes.

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Year:  1995        PMID： 7779254     DOI： 10.1016/0167-5699(95)80166-9

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  80 in total

1.  Characterisation of a mouse monoclonal anti-idiotype reactive with a V region sequence commonly used by human immunoglobulins.

Authors:  J E McElveen; P B Furtado; S J Smith; M R Clark; I Spendlove; H F Sewell; F Shakib
Journal:  Mol Pathol       Date:  2000-04

2.  Histological and immunoglobulin VH gene analysis of interfollicular small lymphocytic lymphoma provides evidence for two types.

Authors:  D W Bahler; N S Aguilera; C C Chen; S L Abbondanzo; S H Swerdlow
Journal:  Am J Pathol       Date:  2000-10       Impact factor: 4.307

3.  Mutation analysis of IgVH gene in B-cell chronic lymphocytic leukemia.

Authors:  Feng Wang; Huifen Zhu; Lijuan Zhu; Botao Yin; Guanxin Shen
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2002

4.  The role of somatic mutation in determining the affinity of anti-DNA antibodies.

Authors:  M Behrendt; L J Partridge; B Griffiths; M Goodfield; M Snaith; N J Lindsey
Journal:  Clin Exp Immunol       Date:  2003-01       Impact factor: 4.330

5.  Splenic marginal zone lymphomas appear to originate from different B cell types.

Authors:  David W Bahler; J Ander Pindzola; Steven H Swerdlow
Journal:  Am J Pathol       Date:  2002-07       Impact factor: 4.307

6.  Analysis of immunoglobulin E VH transcripts in a bronchial biopsy of an asthmatic patient confirms bias towards VH5, and indicates local clonal expansion, somatic mutation and isotype switch events.

Authors:  R E Snow; R Djukanovic; F K Stevenson
Journal:  Immunology       Date:  1999-12       Impact factor: 7.397

7.  Identification of cation-independent mannose 6-phosphate receptor/insulin-like growth factor type-2 receptor as a novel target of autoantibodies.

Authors:  D Tarrago; I Aguilera; J Melero; I Wichmann; A Nuñez-Roldan; B Sanchez
Journal:  Immunology       Date:  1999-12       Impact factor: 7.397

Review 8.  Prognostic usage of V(H) gene mutation status and its surrogate markers and the role of antigen selection in chronic lymphocytic leukemia.

Authors:  Gerard Tobin; Richard Rosenquist
Journal:  Med Oncol       Date:  2005       Impact factor: 3.064

9.  Minimal disease assessment in the treatment of children and adolescents with intermediate-risk (Stage III/IV) B-cell non-Hodgkin lymphoma: a children's oncology group report.

Authors:  Bruce Shiramizu; Stanton Goldman; Ian Kusao; Melissa Agsalda; James Lynch; Lynette Smith; Lauren Harrison; Erin Morris; Thomas G Gross; Warren Sanger; Sherrie Perkins; Mitchell S Cairo
Journal:  Br J Haematol       Date:  2011-04-18       Impact factor: 6.998

10.  Preferential use of the VH5-51 gene segment by the human immune response to code for antibodies against the V3 domain of HIV-1.

Authors:  Miroslaw K Gorny; Xiao-Hong Wang; Constance Williams; Barbara Volsky; Kathy Revesz; Bradley Witover; Sherri Burda; Mateusz Urbanski; Phillipe Nyambi; Chavdar Krachmarov; Abraham Pinter; Susan Zolla-Pazner; Arthur Nadas
Journal:  Mol Immunol       Date:  2008-10-25       Impact factor: 4.407
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