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Literature DB >> 7779253

An important role for intestinally derived T cells in respiratory defence.

Abstract

Margaret Dunkley, Reinhard Pabst and Allan Cripps discuss the role of intestinally derived T cells in protecting the lung against Gram-negative bacterial infection. They describe the factors directing T-cell migration from gut-associated lymphoid tissue to lung, and focus on the role of T cells and T-cell-derived cytokines in bacterial clearance from the lung.

Entities: Disease

Mesh：

Year: 1995 PMID： 7779253 DOI： 10.1016/0167-5699(95)80165-0

Source DB: PubMed Journal: Immunol Today ISSN： 0167-5699

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Cited

16 in total

1. CD8+ T cells have an essential role in pulmonary clearance of nontypeable Haemophilus influenzae following mucosal immunization.

Authors: A R Foxwell; J M Kyd; G Karupiah; A W Cripps
Journal: Infect Immun Date: 2001-04 Impact factor: 3.441

2. Characterization of the gene encoding a 26-kilodalton protein (OMP26) from nontypeable Haemophilus influenzae and immune responses to the recombinant protein.

Authors: W El-Adhami; J M Kyd; D A Bastin; A W Cripps
Journal: Infect Immun Date: 1999-04 Impact factor: 3.441

Review 3. Nasal lymphoid tissue, intranasal immunization, and compartmentalization of the common mucosal immune system.

Authors: H Y Wu; M W Russell
Journal: Immunol Res Date: 1997 Impact factor: 2.829

4. Protection against pulmonary infection with Pseudomonas aeruginosa following immunization with P. aeruginosa-pulsed dendritic cells.

Authors: S Worgall; T Kikuchi; R Singh; K Martushova; L Lande; R G Crystal
Journal: Infect Immun Date: 2001-07 Impact factor: 3.441

5. Proliferating macrophages, dendritic cells, natural killer cells, T and B lymphocytes in the middle ear and Eustachian tube mucosa during experimental acute otitis media in the rat.

Authors: P Jecker; R Pabst; J Westermann
Journal: Clin Exp Immunol Date: 2001-12 Impact factor: 4.330

An important role for intestinally derived T cells in respiratory defence.

1. CD8+ T cells have an essential role in pulmonary clearance of nontypeable Haemophilus influenzae following mucosal immunization.

2. Characterization of the gene encoding a 26-kilodalton protein (OMP26) from nontypeable Haemophilus influenzae and immune responses to the recombinant protein.

Review 3. Nasal lymphoid tissue, intranasal immunization, and compartmentalization of the common mucosal immune system.

4. Protection against pulmonary infection with Pseudomonas aeruginosa following immunization with P. aeruginosa-pulsed dendritic cells.

5. Proliferating macrophages, dendritic cells, natural killer cells, T and B lymphocytes in the middle ear and Eustachian tube mucosa during experimental acute otitis media in the rat.

6. Quantification of proliferating lymphocyte subsets appearing in the intestinal lymph and the blood.

7. Oral non-typable Haemophilus influenzae enhances physiological mechanism of airways protection.

8. Lung phagocyte bactericidal function in strains of mice resistant and susceptible to Pseudomonas aeruginosa.

9. Interleukin-4 enhances pulmonary clearance of Pseudomonas aeruginosa.

Review 10. Lymphocytes in the lung: an often neglected cell. Numbers, characterization and compartmentalization.