Literature DB >> 7779251

Polarization of Th-cell responses: a phylogenetic consequence of nonspecific immune defence?

P Garside1, A M Mowat.   

Abstract

CD4+ T helper (Th)-cell responses are polarized into Th1 and Th2 types. Here, Paul Garside and Allan McI. Mowat propose that this is an evolutionary consequence of the relationship between specific adaptive immunity, individual components of the nonspecific inflammatory response and different types of infection. This concept has important implications both for understanding protective immunity and for vaccine design and delivery.

Entities:  

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Year:  1995        PMID： 7779251     DOI： 10.1016/0167-5699(95)80162-6

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  11 in total

1.  Requirement for splenic CD4+ T cells in the immune privilege of the anterior chamber of the eye.

Authors:  M Takahashi; N Ishimaru; K Yanagi; K Saegusa; N Haneji; H Shiota; Y Hayashi
Journal:  Clin Exp Immunol       Date:  1999-05       Impact factor: 4.330

2.  mRNA expression of cytokines and its impact on outcomes after infection with lethal and nonlethal Plasmodium vinckei parasites.

Authors:  Arif J Siddiqui; Jyoti Bhardwaj; Sunil K Puri
Journal:  Parasitol Res       Date:  2011-10-01       Impact factor: 2.289

3.  Oligoadenylate synthetase/protein kinase R pathways and alphabeta TCR+ T cells are required for adenovirus vector: IFN-gamma inhibition of herpes simplex virus-1 in cornea.

Authors:  Bobbie Ann Austin; William P Halford; Bryan R G Williams; Daniel J J Carr
Journal:  J Immunol       Date:  2007-04-15       Impact factor: 5.422

4.  Host immune response is severely compromised during lethal Plasmodium vinckei infection.

Authors:  Jyoti Bhardwaj; Arif Jamal Siddiqui; Manish Goyal; Kirtika Prakash; Awakash Soni; Sunil K Puri; Mrigank Srivastava
Journal:  Parasitol Res       Date:  2015-06-17       Impact factor: 2.289

5.  Induction of cytokine gene expression by listeriolysin O and roles of macrophages and NK cells.

Authors:  T Nishibori; H Xiong; I Kawamura; M Arakawa; M Mitsuyama
Journal:  Infect Immun       Date:  1996-08       Impact factor: 3.441

6.  Role of Th1 and Th2 cells in anterior chamber-associated immune deviation.

Authors:  X Y Li; L T D'Orazio; J Y Niederkorn
Journal:  Immunology       Date:  1996-09       Impact factor: 7.397

7.  Early gamma interferon responses in lethal and nonlethal murine blood-stage malaria.

Authors:  J B De Souza; K H Williamson; T Otani; J H Playfair
Journal:  Infect Immun       Date:  1997-05       Impact factor: 3.441

8.  Administration of killed bacteria together with listeriolysin O induces protective immunity against Listeria monocytogenes in mice.

Authors:  H Xiong; Y Tanabe; S Ohya; M Mitsuyama
Journal:  Immunology       Date:  1998-05       Impact factor: 7.397

9.  Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells.

Authors:  B Zhang; T Yamamura; T Kondo; M Fujiwara; T Tabira
Journal:  J Exp Med       Date:  1997-11-17       Impact factor: 14.307

10.  Acupuncture regulates leukocyte subpopulations in human peripheral blood.

Authors:  Nobuo Yamaguchi; Takashi Takahashi; Masahiro Sakuma; Toshiroh Sugita; Kumiko Uchikawa; Satoshi Sakaihara; Tsugiyasu Kanda; Matsuo Arai; Kenji Kawakita
Journal:  Evid Based Complement Alternat Med       Date:  2007-12       Impact factor: 2.629
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