| Literature DB >> 7778883 |
R Ross1.
Abstract
The process of atherosclerosis is a life-threatening disease that affects critical organs including the heart and brain. It results from the influence of noxious agents associated with hyperlipidemia, hypertension, diabetes, cigarette smoking, homocysteinemia, and other agents that may, in altering the homeostatic condition of the artery wall, injure the endothelium and smooth muscle. The result is a protective, inflammatory, fibroproliferative response that becomes excessive and in its excess results in the disease process we call atherosclerosis.Entities:
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Year: 1995 PMID： 7778883 DOI： 10.1146/annurev.ph.57.030195.004043
Source DB: PubMed Journal: Annu Rev Physiol ISSN： 0066-4278 Impact factor: 19.318