Literature DB >> 7777149

Influence of dilantin on the reactions of neurons of the visual cortex and the behavior of rabbits during learning.

G I Shul'gina1.   

Abstract

Changes in behavior in response to light flashes, the conditional stimulus of a defense reflex, were not observed following the administration of dilantin, a preparation which attenuates posttetanic potentiation, in rabbits with preliminarily developed defense and inhibitory conditioned reflexes; weak disinhibition of movements appeared in response to the action of flashes against the background of a conditional inhibitor. The similarity of the reactions of the neurons of the visual cortex to light flashes, the CS, with the responses to their joint action with the reinforcement, did not weaken in the majority of instances, while in several neurons, it intensified. The differences in the responses to reinforced and inhibitory light flashes did not disappear following the administration of dilantin, but they attenuated in some of the neurons due to filling of the inhibitory pause with impulses. The results obtained make it possible to draw the conclusion that posttetanic potentiation does not participate in the maintenance of developed conditioned reflexes.

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Year:  1995        PMID: 7777149     DOI: 10.1007/bf02359244

Source DB:  PubMed          Journal:  Neurosci Behav Physiol        ISSN: 0097-0549


  13 in total

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Journal:  J Pharmacol Exp Ther       Date:  1957-07       Impact factor: 4.030

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5.  Inhibitory modulation of long-term potentiation: evidence for a postsynaptic locus of control.

Authors:  R M Douglas; G V Goddard; M Riives
Journal:  Brain Res       Date:  1982-05-27       Impact factor: 3.252

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Journal:  J Physiol       Date:  1978-11       Impact factor: 5.182

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Authors:  G I Shul'gina; A P Petrishcheva; G G Kuznetsova
Journal:  Zh Vyssh Nerv Deiat Im I P Pavlova       Date:  1985 Jul-Aug       Impact factor: 0.437

8.  On the mechanism by which phenytoin blocks post-tetanic potentiation at the frog neuromuscular junction.

Authors:  M E Selzer; G David; Y Yaari
Journal:  J Neurosci       Date:  1985-11       Impact factor: 6.167

9.  The mechanism of action of diphenylhydantoin on invertebrate neurons. II. Effects on synaptic mechanisms.

Authors:  G F Ayala; D Johnston; S Lin; H N Dichter
Journal:  Brain Res       Date:  1977-02       Impact factor: 3.252

10.  Calmodulin systems in neuronal excitability: a molecular approach to epilepsy.

Authors:  R J DeLorenzo
Journal:  Ann Neurol       Date:  1984       Impact factor: 10.422

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