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Literature DB >> 7775195

Immunohistochemical profile of ovarian inclusion cysts in patients with and without ovarian carcinoma.

Abstract

The expression of cytokeratin, epithelial membrane antigen, Leu-M1, B72.3, carcinoembryonic antigen, human placental lactogen, proliferating cell nuclear antigen, p53, and ovarian carcinoma-associated antigen OC-125 was evaluated in inclusion cysts in contralateral ovaries of patients with unilateral ovarian carcinoma. The findings were compared with the findings in inclusion cysts in ovaries of patients without ovarian carcinoma. Although there was more frequent expression of tumour markers B72.3 and CEA in patients with ovarian carcinoma, these differences did not reach statistical significance.

Entities: Disease Gene Species

Mesh：

Substances：
Biomarkers, Tumor

Year: 1995 PMID： 7775195 DOI： 10.1007/bf00243906

Source DB: PubMed Journal: Histochem J ISSN： 0018-2214

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References

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Immunohistochemical profile of ovarian inclusion cysts in patients with and without ovarian carcinoma.

1. Ovarian cystomas of germinal epithelial origin; a histogenetic classification.

2. Immunohistochemistry in the differential diagnosis in the second-look operation for ovarian carcinomas.

3. Is conservative therapy ever justified in stage I (IA) cancer of the ovary?

4. Cancer of the ovary. Survival studies based upon operative therapy, chemotherapy, and radiotherapy.

5. Comparative immunohistochemical study of four monoclonal antibodies directed against ovarian carcinoma-associated antigens.

6. p53 overexpression in formalin-fixed, paraffin-embedded tissue detected by immunohistochemistry.

7. Tumor markers in inclusion cysts of the ovary.

8. The pathogenesis of ovarian inclusion cysts and cystomas.

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10. High incidence of p53 gene mutation in human ovarian cancer and its association with nuclear accumulation of p53 protein and tumor DNA aneuploidy.