A A Orhue1. 1. Department of Obstetrics and Gynaecology, College of Health Sciences, University of Benin, Edo State, Nigeria.
Abstract
OBJECTIVE: To determine which of three methods of induction of labour at term in primigravidae with a low Bishop's score is effective and safe. DESIGN: Random allocation to Prostin E2 and amniotomy later (Group A); low amniotomy and oxytocin titration (Group B); and intra-cervical Foley balloon overnight followed next morning by low amniotomy and oxytocin titration (Group C). SUBJECTS AND SETTING: Primigravidae (n = 90) in the University Hospitals, Benin City, Nigeria. MAIN OUTCOME MEASURE: (i) Time taken to achieve 3 uterine contractions in 10 min; (ii) induction-delivery interval. RESULTS: The mean time interval between intervention and regular uterine contractions was shortest in Group C (A vs. C, P < 0.02; A vs. B, P < 0.02). The mean induction-delivery interval was shortest in Group C (11.1 h) followed by Group B (13.9 h) and Group C (17.9 h) P < 0.05-0.001. CONCLUSION: The induction-delivery interval was shortest when using a Foley catheter for cervical ripening followed by amniotomy and oxytocin titration.
RCT Entities:
OBJECTIVE: To determine which of three methods of induction of labour at term in primigravidae with a low Bishop's score is effective and safe. DESIGN: Random allocation to Prostin E2 and amniotomy later (Group A); low amniotomy and oxytocin titration (Group B); and intra-cervical Foley balloon overnight followed next morning by low amniotomy and oxytocin titration (Group C). SUBJECTS AND SETTING: Primigravidae (n = 90) in the University Hospitals, Benin City, Nigeria. MAIN OUTCOME MEASURE: (i) Time taken to achieve 3 uterine contractions in 10 min; (ii) induction-delivery interval. RESULTS: The mean time interval between intervention and regular uterine contractions was shortest in Group C (A vs. C, P < 0.02; A vs. B, P < 0.02). The mean induction-delivery interval was shortest in Group C (11.1 h) followed by Group B (13.9 h) and Group C (17.9 h) P < 0.05-0.001. CONCLUSION: The induction-delivery interval was shortest when using a Foley catheter for cervical ripening followed by amniotomy and oxytocin titration.
Authors: Marieke Dt de Vaan; Mieke Lg Ten Eikelder; Marta Jozwiak; Kirsten R Palmer; Miranda Davies-Tuck; Kitty Wm Bloemenkamp; Ben Willem J Mol; Michel Boulvain Journal: Cochrane Database Syst Rev Date: 2019-10-18