STUDY OBJECTIVE: To report the occurrence of persistent respiratory disorders, including irritant-induced asthma, among adults living and working near an environmental spill of the pesticide, metam sodium, after the derailment of a tank car. DESIGN: Retrospective clinical case series. SETTING: California communities situated within one-half mile of the Sacramento River, from Mt. Shasta City to Shasta Lake. PATIENTS: 197 adults referred to a university occupational/environmental health clinic or to a private occupational/environmental health practitioner for evaluation of health problems potentially related to the spill. MEASUREMENTS AND RESULTS: History, physical examination, review of medical records, spirometry, and methacholine challenge testing revealed 20 cases of persistent irritant-induced asthma and 10 cases of persistent exacerbation of asthma. CONCLUSIONS: This is the first reported series of cases of persistent irritant-induced asthma involving both community residents and occupationally exposed individuals.
STUDY OBJECTIVE: To report the occurrence of persistent respiratory disorders, including irritant-induced asthma, among adults living and working near an environmental spill of the pesticide, metam sodium, after the derailment of a tank car. DESIGN: Retrospective clinical case series. SETTING: California communities situated within one-half mile of the Sacramento River, from Mt. Shasta City to Shasta Lake. PATIENTS: 197 adults referred to a university occupational/environmental health clinic or to a private occupational/environmental health practitioner for evaluation of health problems potentially related to the spill. MEASUREMENTS AND RESULTS: History, physical examination, review of medical records, spirometry, and methacholine challenge testing revealed 20 cases of persistent irritant-induced asthma and 10 cases of persistent exacerbation of asthma. CONCLUSIONS: This is the first reported series of cases of persistent irritant-induced asthma involving both community residents and occupationally exposed individuals.
Authors: Gisela I Banauch; Charles Hall; Michael Weiden; Hillel W Cohen; Thomas K Aldrich; Vasillios Christodoulou; Nicole Arcentales; Kerry J Kelly; David J Prezant Journal: Am J Respir Crit Care Med Date: 2006-04-27 Impact factor: 21.405
Authors: Bret F Bessac; Michael Sivula; Christian A von Hehn; Ana I Caceres; Jasmine Escalera; Sven-Eric Jordt Journal: FASEB J Date: 2008-11-26 Impact factor: 5.191
Authors: Robert B Gunier; Rachel Raanan; Rosemary Castorina; Nina T Holland; Kim G Harley; John R Balmes; Laura Fouquette; Brenda Eskenazi; Asa Bradman Journal: Environ Res Date: 2018-02-23 Impact factor: 6.498
Authors: Mark Farfel; Laura DiGrande; Robert Brackbill; Angela Prann; James Cone; Stephen Friedman; Deborah J Walker; Grant Pezeshki; Pauline Thomas; Sandro Galea; David Williamson; Thomas R Frieden; Lorna Thorpe Journal: J Urban Health Date: 2008-09-11 Impact factor: 3.671