Literature DB >> 7773004

Molecular genetics of neuronal survival.

I Silos-Santiago1, L J Greenlund, E M Johnson, W D Snider.   

Abstract

The past year has witnessed remarkable progress towards understanding the molecular genetics of neuronal survival. Gene-targeting experiments in mice have confirmed the long-standing idea that the nerve growth factor model of neuronal survival--that is, neuronal dependence on target-derived molecules during a critical period in development--is broadly applicable. Furthermore, a variety of biochemical and genetic techniques applied to both mammals and invertebrates have identified new genes involved in regulating cell survival during development.

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Year:  1995        PMID： 7773004     DOI： 10.1016/0959-4388(95)80085-9

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN： 0959-4388            Impact factor:   6.627


  11 in total

1.  Neurotrophic factors in neurodegenerative disorders: model of Parkinson's disease.

Authors:  J Garcia de Yebenes; J Yebenes; M A Mena
Journal:  Neurotox Res       Date:  2000       Impact factor: 3.911

2.  PDCD10/CCM3 acts downstream of {gamma}-protocadherins to regulate neuronal survival.

Authors:  Chengyi Lin; Shuxia Meng; Tina Zhu; Xiaozhong Wang
Journal:  J Biol Chem       Date:  2010-11-01       Impact factor: 5.157

3.  Differential survival of Cajal-Retzius cells in organotypic cultures of hippocampus and neocortex.

Authors:  J A Del Río; B Heimrich; H Supèr; V Borrell; M Frotscher; E Soriano
Journal:  J Neurosci       Date:  1996-11-01       Impact factor: 6.167

4.  Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system.

Authors:  K F Macleod; Y Hu; T Jacks
Journal:  EMBO J       Date:  1996-11-15       Impact factor: 11.598

5.  NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking.

Authors:  E C Beattie; C L Howe; A Wilde; F M Brodsky; W C Mobley
Journal:  J Neurosci       Date:  2000-10-01       Impact factor: 6.167

6.  Numb modifies neuronal vulnerability to amyloid beta-peptide in an isoform-specific manner by a mechanism involving altered calcium homeostasis: implications for neuronal death in Alzheimer's disease.

Authors:  Sic L Chan; Ward A Pedersen; Hiayan Zhu; Mark P Mattson
Journal:  Neuromolecular Med       Date:  2002       Impact factor: 3.843

7.  The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons.

Authors:  Ditsa Levanon; David Bettoun; Catherine Harris-Cerruti; Eilon Woolf; Varda Negreanu; Raya Eilam; Yael Bernstein; Dalia Goldenberg; Cuiying Xiao; Manfred Fliegauf; Eitan Kremer; Florian Otto; Ori Brenner; Aharon Lev-Tov; Yoram Groner
Journal:  EMBO J       Date:  2002-07-01       Impact factor: 11.598

8.  Requirement of 3-phosphoinositide-dependent protein kinase-1 for BDNF-mediated neuronal survival.

Authors:  Giorgi Kharebava; Denys Makonchuk; Katarzyna B Kalita; Jing-Juan Zheng; Michal Hetman
Journal:  J Neurosci       Date:  2008-10-29       Impact factor: 6.167

9.  Axonal transport blockade in the neonatal rat optic nerve induces limited retinal ganglion cell death.

Authors:  M Fagiolini; M Caleo; E Strettoi; L Maffei
Journal:  J Neurosci       Date:  1997-09-15       Impact factor: 6.167

10.  Blocking cytochrome c activity within intact neurons inhibits apoptosis.

Authors:  S J Neame; L L Rubin; K L Philpott
Journal:  J Cell Biol       Date:  1998-09-21       Impact factor: 10.539
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