| Literature DB >> 7772237 |
S Palmero1, P De Marco, E Fugassa.
Abstract
A polymerase chain reaction (PCR)-based assay was used to evaluate the expression of thyroid hormone receptor beta mRNA in Sertoli cells isolated from both prepubertal rat and piglet testes. The expression of an mRNA coding for the functional thyroid hormone receptor beta isoform, as established by the PCR assay, agrees with the presence of specific tri-iodothyronine (T3) -binding sites in the Sertoli cell nuclei of both species, as previously evaluated by displacement analysis. The results ratify the existence of a functional T3 receptor in the prepubertal testis and confirm the Sertoli cell as a specific target for thyroid hormone action on the developing testis.Entities:
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Year: 1995 PMID： 7772237 DOI： 10.1677/jme.0.0140131
Source DB: PubMed Journal: J Mol Endocrinol ISSN： 0952-5041 Impact factor: 5.098