Literature DB >> 7770614

Effects of lorazepam on human contrast sensitivity.

J P Haris1, O T Phillipson.   

Abstract

The anxiolytic lorazepam was studied for its effects on contrast sensitivity to gratings flickering in counterphase in normal volunteers. The drug significantly reduced contrast sensitivity at low spatial frequencies in a dose-related manner. The results are discussed with reference to possible GABA-mediated processes in the retina and lateral geniculate nucleus.

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Year:  1995        PMID： 7770614     DOI： 10.1007/bf02246113

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  23 in total

1.  Psychophysical evidence for sustained and transient detectors in human vision.

Authors:  J J Kulikowski; D J Tolhurst
Journal:  J Physiol       Date:  1973-07       Impact factor: 5.182

2.  On the existence of neurones in the human visual system selectively sensitive to the orientation and size of retinal images.

Authors:  C Blakemore; F W Campbell
Journal:  J Physiol       Date:  1969-07       Impact factor: 5.182

3.  The proportion and size of GABA-immunoreactive neurons in the magnocellular and parvocellular layers of the lateral geniculate nucleus of the rhesus monkey.

Authors:  V M Montero; J Zempel
Journal:  Exp Brain Res       Date:  1986       Impact factor: 1.972

4.  The effect of spatial adaptation on perceived contrast.

Authors:  M A Georgeson
Journal:  Spat Vis       Date:  1985

Review 5.  The GABA-ergic system: a locus of benzodiazepine action.

Authors:  J F Tallman; D W Gallager
Journal:  Annu Rev Neurosci       Date:  1985       Impact factor: 12.449

6.  The functional area for summation to threshold for sinusoidal gratings.

Authors:  E R Howell; R F Hess
Journal:  Vision Res       Date:  1978       Impact factor: 1.886

7.  Contrast adaptation in cat visual cortex is not mediated by GABA.

Authors:  E J DeBruyn; A B Bonds
Journal:  Brain Res       Date:  1986-09-24       Impact factor: 3.252

8.  Effects of intravenous diazepam (valium) upon evoked potentials of photosensitive epileptic and normal subjects.

Authors:  M Ebe; K H Meier-Ewert; R Broughton
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1969-10

9.  Evaluation of signal detection theory on the effects of psychotropic drugs on critical flicker-fusion frequency in normal subjects.

Authors:  M W MacNab; E L Foltz; J Sweitzer
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

10.  The role of gamma-aminobutyric acid mediated inhibition in the response properties of cat lateral geniculate nucleus neurones.

Authors:  N Berardi; M C Morrone
Journal:  J Physiol       Date:  1984-12       Impact factor: 5.182
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  4 in total

1.  Impairment of contrast sensitivity in long-term lorazepam users.

Authors:  Anne Giersch; Claude Speeg-Schatz; Monique Tondre; Sylvaine Gottenkiene
Journal:  Psychopharmacology (Berl)       Date:  2006-04-04       Impact factor: 4.530

2.  Enhanced distraction by magnocellular salience signals in schizophrenia.

Authors:  Carly J Leonard; Benjamin M Robinson; Britta Hahn; James M Gold; Steven J Luck
Journal:  Neuropsychologia       Date:  2014-02-18       Impact factor: 3.139

3.  Lorazepam impairs perceptual integration of visual forms: a central effect.

Authors:  A Giersch; M Boucart; C Speeg-Schatz; F Muller-Kauffmann; J M Danion
Journal:  Psychopharmacology (Berl)       Date:  1996-08       Impact factor: 4.530

4.  Low Spatial Frequency Bias in Schizophrenia is Not Face Specific: When the Integration of Coarse and Fine Information Fails.

Authors:  Vincent Laprevote; Aude Oliva; Anne-Sophie Ternois; Raymund Schwan; Pierre Thomas; Muriel Boucart
Journal:  Front Psychol       Date:  2013-05-06
  4 in total

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