Literature DB >> 7769821

Amplification of responses to sumatriptan by various agonists in rabbit isolated iliac artery.

O Yildiz1, M Tuncer.   

Abstract

Rabbit iliac arteries (IA) were almost unresponsive to the serotonin (5-HT1-like) receptor agonist sumatriptan under control conditions, whereas this agent elicited concentration-dependent contractions in IA rings given a moderate tone by threshold concentrations (EC10-EC20) of prostaglandin F2 alpha (PGF2 alpha), angiotensin II (AII), histamine, norepinephrine (NE), phenylephrine (PE), or potassium chloride. These results suggest that 5-HT1-like receptors are uncovered not only by histamine or thromboxane/prostaglandin receptor agonists, as shown in rabbit renal and femoral arteries, but also by various agonists in rabbit IA as shown in this study.

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Year:  1995        PMID： 7769821     DOI： 10.1097/00005344-199503000-00025

Source DB:  PubMed          Journal:  J Cardiovasc Pharmacol        ISSN： 0160-2446            Impact factor:   3.105


  7 in total

1.  The involvement of intracellular Ca(2+) in 5-HT(1B/1D) receptor-mediated contraction of the rabbit isolated renal artery.

Authors:  P B Hill; K A Dora; A D Hughes; C J Garland
Journal:  Br J Pharmacol       Date:  2000-06       Impact factor: 8.739

2.  Functional characterization and m-RNA expression of 5-HT receptors mediating contraction in human umbilical artery.

Authors:  F Lovren; X F Li; J Lytton; C Triggle
Journal:  Br J Pharmacol       Date:  1999-07       Impact factor: 8.739

3.  Augmented contraction of the human isolated coronary artery by sumatriptan: a possible role for endogenous thromboxane.

Authors:  A Maassen VanDenBrink; W A Bax; M D Ferrari; F J Zijlstra; E Bos; P R Saxena
Journal:  Br J Pharmacol       Date:  1996-11       Impact factor: 8.739

4.  Collar-induced elevation of mRNA and functional activity of 5-HT(1B) receptor in the rabbit carotid artery.

Authors:  I S Geerts; G R De Meyer; H Bult
Journal:  Br J Pharmacol       Date:  2000-12       Impact factor: 8.739

5.  Contractile responses to sumatriptan and ergotamine in the rabbit saphenous vein: effect of selective 5-HT(1F) receptor agonists and PGF(2alpha).

Authors:  M L Cohen; K Schenck
Journal:  Br J Pharmacol       Date:  2000-10       Impact factor: 8.739

6.  5-HT1-like and 5-HT2A receptors mediate 5-hydroxytryptamine-induced contraction of rabbit isolated mesenteric artery.

Authors:  O Yildiz; M Tuncer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1995-08       Impact factor: 3.000

7.  Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery.

Authors:  S Jähnichen; O A Radtke; H H Pertz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2004-06-08       Impact factor: 3.000
  7 in total

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