Literature DB >> 7769392

Varacin and three new marine antimicrobial polysulfides from the far-eastern ascidian Polycitor sp.

T N Makarieva1, V A Stonik, A S Dmitrenok, B B Grebnev, V V Isakov, N M Rebachyk, Y W Rashkes.   

Abstract

Varacin [1] and three new antimicrobial marine polysulfides, varacins A-C [3-5], have been isolated from the Far Eastern ascidian Polycitor sp. Their structures have been elucidated by spectroscopic methods and by chemical transformations.

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Year:  1995        PMID： 7769392     DOI： 10.1021/np50116a015

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  10 in total

1.  Synthesis, characterization, mechanism of decomposition, and antiproliferative activity of a class of PEGylated benzopolysulfanes structurally similar to the natural product varacin.

Authors:  Adaickapillai Mahendran; Angela Vuong; David Aebisher; Yaqiong Gong; Robert Bittman; Gilbert Arthur; Akira Kawamura; Alexander Greer
Journal:  J Org Chem       Date:  2010-08-20       Impact factor: 4.354

2.  Synthesis and antiproliferative properties of a new ceramide analog of varacin.

Authors:  Adaickapillai Mahendran; Ashwini A Ghogare; Robert Bittman; Gilbert Arthur; Alexander Greer
Journal:  Chem Phys Lipids       Date:  2015-08-05       Impact factor: 3.329

3.  Varacin-1, a novel analog of varacin C, induces p53-independent apoptosis in cancer cells through ROS-mediated reduction of XIAP.

Authors:  Jing Zhou; Wen-Li Li; Zi-Xuan Wang; Nai-Yuan Chen; Yue Tang; Xiao-Xiao Hu; Jing-Huan Deng; Yixin Lu; Guo-Dong Lu
Journal:  Acta Pharmacol Sin       Date:  2018-05-17       Impact factor: 6.150

4.  Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53.

Authors:  Jason A Clement; Jirouta Kitagaki; Yili Yang; Carrie J Saucedo; Barry R O'Keefe; Allan M Weissman; Tawnya C McKee; James B McMahon
Journal:  Bioorg Med Chem       Date:  2008-10-14       Impact factor: 3.641

5.  Aplisulfamines, new sulfoxide-containing metabolites from an aplidium tunicate: absolute stereochemistry at chiral sulfur and carbon atoms assigned through an original combination of spectroscopic and computational methods.

Authors:  Anna Aiello; Ernesto Fattorusso; Concetta Imperatore; Paolo Luciano; Marialuisa Menna; Rocco Vitalone
Journal:  Mar Drugs       Date:  2012-01-04       Impact factor: 6.085

6.  Marine natural products: a way to new drugs.

Authors:  V A Stonik
Journal:  Acta Naturae       Date:  2009-07       Impact factor: 1.845

7.  Marine natural products acting on the acetylcholine-binding protein and nicotinic receptors: from computer modeling to binding studies and electrophysiology.

Authors:  Denis Kudryavtsev; Tatyana Makarieva; Natalia Utkina; Elena Santalova; Elena Kryukova; Christoph Methfessel; Victor Tsetlin; Valentin Stonik; Igor Kasheverov
Journal:  Mar Drugs       Date:  2014-03-28       Impact factor: 5.118

8.  Polysulfurating reagent design for unsymmetrical polysulfide construction.

Authors:  Xiao Xiao; Jiahui Xue; Xuefeng Jiang
Journal:  Nat Commun       Date:  2018-06-06       Impact factor: 14.919

9.  Pentathiepins: A Novel Class of Glutathione Peroxidase 1 Inhibitors that Induce Oxidative Stress, Loss of Mitochondrial Membrane Potential and Apoptosis in Human Cancer Cells.

Authors:  Steven Behnisch-Cornwell; Siva Sankar Murthy Bandaru; Martin Napierkowski; Lisa Wolff; Muhammad Zubair; Claudia Urbainsky; Christopher Lillig; Carola Schulzke; Patrick J Bednarski
Journal:  ChemMedChem       Date:  2020-05-06       Impact factor: 3.466

10.  A novel alkaloid from marine-derived actinomycete Streptomyces xinghaiensis with broad-spectrum antibacterial and cytotoxic activities.

Authors:  Wence Jiao; Fenghua Zhang; Xinqing Zhao; Jiehan Hu; Joo-Won Suh
Journal:  PLoS One       Date:  2013-10-01       Impact factor: 3.240
  10 in total

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