Literature DB >> 7769386

In vivo and in vitro biosynthesis of saponins in sea cucumbers.

R G Kerr1, Z Chen.   

Abstract

The triterpene precursor of saponins in sea cucumbers has been identified as parkeol [lanost-9(11)-en-3 beta-ol] [1]. Dissection of the sea cucumbers Holothuria floridea and Actinopyga agassize after incubations with radiolabeled parkeol demonstrated that saponin biosynthesis occurs exclusively in the Cuvier gland. This result was corroborated by incubating a cell-free extract of the Cuvier gland with labeled parkeol and observing transformation of the precursor to saponins.

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Year:  1995        PMID： 7769386     DOI： 10.1021/np50116a002

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  17 in total

1.  De novo genome assembly and annotation of Holothuria scabra (Jaeger, 1833) from nanopore sequencing reads.

Authors:  Honglin Luo; Guanghua Huang; Jianbin Li; Qiong Yang; Jiajie Zhu; Bin Zhang; Pengfei Feng; Yongde Zhang; Xueming Yang
Journal:  Genes Genomics       Date:  2022-10-16       Impact factor: 2.164

Review 2.  High-value components and bioactives from sea cucumbers for functional foods--a review.

Authors:  Sara Bordbar; Farooq Anwar; Nazamid Saari
Journal:  Mar Drugs       Date:  2011-10-10       Impact factor: 6.085

Review 3.  Sea Cucumbers Metabolites as Potent Anti-Cancer Agents.

Authors:  Naveena B Janakiram; Altaf Mohammed; Chinthalapally V Rao
Journal:  Mar Drugs       Date:  2015-05-12       Impact factor: 5.118

4.  Structure elucidation of five novel isomeric saponins from the viscera of the sea cucumber Holothuria lessoni.

Authors:  Yadollah Bahrami; Wei Zhang; Tim Chataway; Chris Franco
Journal:  Mar Drugs       Date:  2014-08-08       Impact factor: 5.118

Review 5.  Relationships between chemical structures and functions of triterpene glycosides isolated from sea cucumbers.

Authors:  Joo-In Park; Hae-Rahn Bae; Chang Gun Kim; Valentin A Stonik; Jong-Young Kwak
Journal:  Front Chem       Date:  2014-09-09       Impact factor: 5.221

6.  Structure elucidation of new acetylated saponins, Lessoniosides A, B, C, D, and E, and non-acetylated saponins, Lessoniosides F and G, from the viscera of the sea cucumber Holothuria lessoni.

Authors:  Yadollah Bahrami; Christopher M M Franco
Journal:  Mar Drugs       Date:  2015-01-16       Impact factor: 5.118

7.  Actinopyga lecanora hydrolysates as natural antibacterial agents.

Authors:  Raheleh Ghanbari; Afshin Ebrahimpour; Azizah Abdul-Hamid; Amin Ismail; Nazamid Saari
Journal:  Int J Mol Sci       Date:  2012-12-07       Impact factor: 5.923

8.  Diterpene glycosides from Holothuria scabra exert the α-synuclein degradation and neuroprotection against α-synuclein-Mediated neurodegeneration in C. elegans model.

Authors:  Pawanrat Chalorak; Nilubon Sornkaew; Preeyanuch Manohong; Nakorn Niamnont; Nawaphat Malaiwong; Tanapol Limboonreung; Prasert Sobhon; Michael Aschner; Krai Meemon
Journal:  J Ethnopharmacol       Date:  2021-06-17       Impact factor: 5.195

9.  Discovery of novel saponins from the viscera of the sea cucumber Holothuria lessoni.

Authors:  Yadollah Bahrami; Wei Zhang; Chris Franco
Journal:  Mar Drugs       Date:  2014-05-09       Impact factor: 5.118

10.  Bioactive compounds from Holothuria atra of Indian ocean.

Authors:  Devaraj Isaac Dhinakaran; Aaron Premnath Lipton
Journal:  Springerplus       Date:  2014-11-14
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