Literature DB >> 7766387

15-hydroperoxydehydroabietic acid--a contact allergen in colophony from pinus species.

L P Shao1, E Gäfvert, U Nilsson, A T Karlberg, J L Nilsson.   

Abstract

A new hydroperoxide, 15-hydroperoxydehydroabietic acid (15-HPDA), with contact allergenic properties has been detected in rosin obtained from Pinus species. Detection was facilitated using a synthetic preparation of 15-HPDA for reference purposes. The synthesis and the detection (HPLC and GC) of 15-HPDA in rosin are described. The allergenic activity of 15-HPDA was studied in an experimental sensitization test on guinea-pigs.

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Year:  1995        PMID: 7766387     DOI: 10.1016/0031-9422(94)00762-i

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  1 in total

1.  EIMS Fragmentation Pathways and MRM Quantification of 7α/β-Hydroxy-Dehydroabietic Acid TMS Derivatives.

Authors:  Jean-François Rontani; Claude Aubert; Simon T Belt
Journal:  J Am Soc Mass Spectrom       Date:  2015-07-03       Impact factor: 3.109

  1 in total

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