| Literature DB >> 7766387 |
L P Shao1, E Gäfvert, U Nilsson, A T Karlberg, J L Nilsson.
Abstract
A new hydroperoxide, 15-hydroperoxydehydroabietic acid (15-HPDA), with contact allergenic properties has been detected in rosin obtained from Pinus species. Detection was facilitated using a synthetic preparation of 15-HPDA for reference purposes. The synthesis and the detection (HPLC and GC) of 15-HPDA in rosin are described. The allergenic activity of 15-HPDA was studied in an experimental sensitization test on guinea-pigs.Entities:
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Year: 1995 PMID: 7766387 DOI: 10.1016/0031-9422(94)00762-i
Source DB: PubMed Journal: Phytochemistry ISSN: 0031-9422 Impact factor: 4.072