Literature DB >> 7766092

Uptake of phenoxyacetic acid by Penicillium chrysogenum.

S H Eriksen1, B Jensen, I Schneider, S Kaasgaard, J Olsen.   

Abstract

The uptake of phenoxyacetic acid by two different strains of Penicillium chrysogenum was studied. Phenoxyacetic acid (POA) was taken up by P. chrysogenum in a defined medium. Plots of initial velocity of POA uptake versus external substrate concentration, in the range 2-5000 microM, gave linear plots. Uptake of POA by induced and uninduced cells was identical. The initial velocity of POA uptake decreased as the pH of the suspension was increased from 5.4 to 7.2; the decrease closely paralleled the decline in the non-ionic form of the acid over this pH range. The initial velocity of POA uptake was not affected by the presence of phenylacetic acid. POA uptake proceeded until the cellular concentration was equal to the external concentration. It is concluded that POA is passively transported into P. chrysogenum by unmediated diffusion.

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Year:  1995        PMID: 7766092     DOI: 10.1007/BF00191195

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN: 0175-7598            Impact factor:   4.813


  10 in total

1.  A new class of uncoupling agents--carbonyl cyanide phenylhydrazones.

Authors:  P G HEYTLER; W W PRICHARD
Journal:  Biochem Biophys Res Commun       Date:  1962-05-04       Impact factor: 3.575

2.  [On the biosynthesis of penicillin. Studies on the enzymatic activation of phenylacetic acid and phenoxyacetic acid as well as the formation of penicillin from 6-aminopenicillanic acid and activated side chain acids by mycelial homogenates and cell-free extracts of Penicillium chrysogenum].

Authors:  R Brunner; M Röhr; M Zinner
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1968-01

3.  Uptake of phenylacetic acid by Penicillium chrysogenum Wis 54-1255: a critical regulatory point in benzylpenicillin biosynthesis.

Authors:  J M Fernández-Cañón; A Reglero; H Martínez-Blanco; J M Luengo
Journal:  J Antibiot (Tokyo)       Date:  1989-09       Impact factor: 2.649

4.  Repression of phenylacetic acid transport system in Penicillium chrysogenum Wis 54-1255 by free amino acids and ammonium salts.

Authors:  H Martínez-Blanco; A Reglero; M A Ferrero; J M Fernández-Cañón; J M Luengo
Journal:  J Antibiot (Tokyo)       Date:  1989-09       Impact factor: 2.649

5.  Phenylacetic acid transport system in Penicillium chrysogenum Wis 54-1255: molecular specificity of its induction.

Authors:  J M Fernández-Cañón; A Reglero; H Martínez-Blanco; M A Ferrero; J M Luengo
Journal:  J Antibiot (Tokyo)       Date:  1989-09       Impact factor: 2.649

6.  Inhibition of membrane transport in Streptococcus faecalis by uncouplers of oxidative phosphorylation and its relationship to proton conduction.

Authors:  F M Harold; J R Baarda
Journal:  J Bacteriol       Date:  1968-12       Impact factor: 3.490

7.  Utilization of side-chain precursors for penicillin biosynthesis in a high-producing strain of Penicillium chrysogenum.

Authors:  S H Eriksen; B Jensen; I Schneider; S Kaasgaard; J Olsen
Journal:  Appl Microbiol Biotechnol       Date:  1994-02       Impact factor: 4.813

8.  Isolation and characterization of the acetyl-CoA synthetase from Penicillium chrysogenum. Involvement of this enzyme in the biosynthesis of penicillins.

Authors:  H Martínez-Blanco; A Reglero; M Fernández-Valverde; M A Ferrero; M A Moreno; M A Peñalva; J M Luengo
Journal:  J Biol Chem       Date:  1992-03-15       Impact factor: 5.157

9.  Subcellular compartmentation of penicillin biosynthesis in Penicillium chrysogenum. The amino acid precursors are derived from the vacuole.

Authors:  T Lendenfeld; D Ghali; M Wolschek; E M Kubicek-Pranz; C P Kubicek
Journal:  J Biol Chem       Date:  1993-01-05       Impact factor: 5.157

10.  Localization of the pathway of the penicillin biosynthesis in Penicillium chrysogenum.

Authors:  W H Müller; T P van der Krift; A J Krouwer; H A Wösten; L H van der Voort; E B Smaal; A J Verkleij
Journal:  EMBO J       Date:  1991-02       Impact factor: 11.598

  10 in total
  1 in total

1.  Penicillin V production by Penicillium chrysogenum in the presence of Fe3+ and in low-iron culture medium.

Authors:  E Leiter; T Emri; G Gyémánt; I Nagy; I Pócsi; G Winkelmann; I Pócsi
Journal:  Folia Microbiol (Praha)       Date:  2001       Impact factor: 2.099

  1 in total

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