Literature DB >> 7765966

Effects of alpha- and beta-arbutin on activity of tyrosinases from mushroom and mouse melanoma.

M Funayama1, H Arakawa, R Yamamoto, T Nishino, T Shin, S Murao.   

Abstract

The effects of alpha- and beta-arbutin on the activity of tyrosinases from mushroom and mouse melanoma were examined. alpha-Arbutin was synthesized from hydroquinone and starch using glucoside synthetase (GSase). beta-Arbutin inhibited both tyrosinase activities from mushroom and mouse melanoma. alpha-Arbutin inhibited only the tyrosinase from mouse melanoma, 10 times as strongly as beta-arbutin. The IC50 of alpha-arbutin was 0.48 mM and its inhibitory mechanism was speculated to be mixed type inhibition, while that of beta-arbutin was noncompetitive.

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Year:  1995        PMID： 7765966     DOI： 10.1271/bbb.59.143

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  22 in total

1.  Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color.

Authors:  Erica C Davis; Valerie D Callender
Journal:  J Clin Aesthet Dermatol       Date:  2010-07

2.  Screening of high α-arbutin producing strains and production of α-arbutin by fermentation.

Authors:  Chun-Qiao Liu; Li Deng; Peng Zhang; Shu-Rong Zhang; Luo Liu; Tao Xu; Fang Wang; Tian-Wei Tan
Journal:  World J Microbiol Biotechnol       Date:  2013-03-01       Impact factor: 3.312

3.  Development and validation of a modified QuEChERS method coupled with LC-MS/MS to determine arbutin in pear peels.

Authors:  Jueun Kim; Jae Il Kim; Chul Won Lee
Journal:  Food Sci Biotechnol       Date:  2016-08-31       Impact factor: 2.391

4.  Enhancement of antioxidative and antimicrobial activities of immature pear (Pyrus pyrifolia cv. Niitaka) fruits by fermentation with Leuconostoc mesenteroides.

Authors:  Sang Won Lee; Jeong-Yong Cho; Hang Yeon Jeong; Tae-Woong Na; Sang-Hyun Lee; Jae-Hak Moon
Journal:  Food Sci Biotechnol       Date:  2016-12-31       Impact factor: 2.391

5.  Anti-inflammatory effects of arbutin in lipopolysaccharide-stimulated BV2 microglial cells.

Authors:  Hyo-Jong Lee; Kyu-Won Kim
Journal:  Inflamm Res       Date:  2012-04-10       Impact factor: 4.575

Review 6.  Actinobacterial melanins: current status and perspective for the future.

Authors:  Panchanathan Manivasagan; Jayachandran Venkatesan; Kannan Sivakumar; Se-Kwon Kim
Journal:  World J Microbiol Biotechnol       Date:  2013-04-18       Impact factor: 3.312

7.  High cell density cultivation of Escherichia coli with surface anchored transglucosidase for use as whole-cell biocatalyst for alpha-arbutin synthesis.

Authors:  Po-Hung Wu; Giridhar R Nair; I-Ming Chu; Wen-Teng Wu
Journal:  J Ind Microbiol Biotechnol       Date:  2007-11-01       Impact factor: 3.346

8.  Discovery of highly potent tyrosinase inhibitor, T1, with significant anti-melanogenesis ability by zebrafish in vivo assay and computational molecular modeling.

Authors:  Wang-Chuan Chen; Tien-Sheng Tseng; Nai-Wan Hsiao; Yun-Lian Lin; Zhi-Hong Wen; Chin-Chuan Tsai; Yu-Ching Lee; Hui-Hsiung Lin; Keng-Chang Tsai
Journal:  Sci Rep       Date:  2015-01-23       Impact factor: 4.379

Review 9.  The hunt for natural skin whitening agents.

Authors:  Nico Smit; Jana Vicanova; Stan Pavel
Journal:  Int J Mol Sci       Date:  2009-12-10       Impact factor: 6.208

10.  Biotransformation of hydroquinone into α-arbutin by transglucosylation activity of a metagenomic amylosucrase.

Authors:  Neera Agarwal; Amit K Rai; Sudhir P Singh
Journal:  3 Biotech       Date:  2021-07-03       Impact factor: 2.893
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