| Literature DB >> 7765428 |
L Rocha1, A Marston, M A Kaplan, H Stoeckli-Evans, U Thull, B Testa, K Hostettmann.
Abstract
A new gamma-pyrone (hyperbrasilone), three known xanthones (1,5-dihydroxyxanthone, 5-hydroxy-1-methoxyxanthone and 6-deoxyjacareubin) and betulinic acid have been isolated from a dichloromethane extract of stems and roots of Hypericum brasiliense. Their structures were established by spectroscopic methods (UV, EI-MS, 1H and 13C NMR) and that of the gamma-pyrone was confirmed by X-ray crystallography. Hyperbrasilone and the xanthones were all antifungal against Cladosporium cucumerinum, while the three xanthones showed differing degrees of inhibition of monoamine oxidase A and B.Entities:
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Year: 1994 PMID： 7765428 DOI： 10.1016/s0031-9422(00)89727-7
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072