Literature DB >> 7765059

Parallel synthesis and analysis of large numbers of related chemical compounds: applications to oligonucleotides.

E M Southern1, U Maskos.   

Abstract

This review presents methods for addressing the issue of molecular complexity in biological systems. Biomolecules immobilised on solid phases can be used to probe biological interactions. As a specific example, arrays of large numbers of oligonucleotides allow the analysis of DNA sequences and complex populations of DNA molecules. The specific embodiments of this new method are presented, research up to mid-1992 outlined and requirements for future development discussed.

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Year:  1994        PMID： 7765059     DOI： 10.1016/0168-1656(94)90037-x

Source DB:  PubMed          Journal:  J Biotechnol        ISSN： 0168-1656            Impact factor:   3.307


  9 in total

1.  Gene expression analysis with universal n-mer arrays.

Authors:  R Michael van Dam; Stephen R Quake
Journal:  Genome Res       Date:  2002-01       Impact factor: 9.043

2.  Oligonucleotide dendrimers: stable nano-structures.

Authors:  M S Shchepinov; K U Mir; J K Elder; M D Frank-Kamenetskii; E M Southern
Journal:  Nucleic Acids Res       Date:  1999-08-01       Impact factor: 16.971

3.  Steric factors influencing hybridisation of nucleic acids to oligonucleotide arrays.

Authors:  M S Shchepinov; S C Case-Green; E M Southern
Journal:  Nucleic Acids Res       Date:  1997-03-15       Impact factor: 16.971

4.  Oligonucleotide dendrimers: synthesis and use as polylabelled DNA probes.

Authors:  M S Shchepinov; I A Udalova; A J Bridgman; E M Southern
Journal:  Nucleic Acids Res       Date:  1997-11-15       Impact factor: 16.971

5.  Melting studies of dangling-ended DNA hairpins: effects of end length, loop sequence and biotinylation of loop bases.

Authors:  Peter V Riccelli; Kathleen E Mandell; Albert S Benight
Journal:  Nucleic Acids Res       Date:  2002-09-15       Impact factor: 16.971

6.  Modern approaches to understanding stress and disease susceptibility: A review with special emphasis on respiratory disease.

Authors:  Palok Aich; Andrew A Potter; Philip J Griebel
Journal:  Int J Gen Med       Date:  2009-07-30

7.  Performance characteristics of 65-mer oligonucleotide microarrays.

Authors:  Myoyong Lee; Charlie C Xiang; Jeffrey M Trent; Michael L Bittner
Journal:  Anal Biochem       Date:  2007-05-13       Impact factor: 3.365

Review 8.  Engineered polymers for advanced drug delivery.

Authors:  Sungwon Kim; Jong-Ho Kim; Oju Jeon; Ick Chan Kwon; Kinam Park
Journal:  Eur J Pharm Biopharm       Date:  2008-10-17       Impact factor: 5.571

Review 9.  Molecular analyses of disease pathogenesis: application of bovine microarrays.

Authors:  Heather L Wilson; Palok Aich; Fiona M Roche; Shakiba Jalal; Paul D Hodgson; Fiona S L Brinkman; Andy Potter; Lorne A Babiuk; Philip J Griebel
Journal:  Vet Immunol Immunopathol       Date:  2005-05-15       Impact factor: 2.046
  9 in total

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