Literature DB >> 7764474

Targeted delivery of toxins and enzymes by antibodies and growth factors.

L L Houston1.   

Abstract

Significant progress has been made in our understanding of some of the important physiological and pharmacological barriers that limit immunoconjugate efficacy. Recent successes obtained employing immunotoxins in the treatment of leukemia and lymphoma in mouse models are suggesting ways of improving clinical strategies to treat these diseases in humans.

Entities:  

Mesh:

Substances:

Year:  1993        PMID: 7764474     DOI: 10.1016/0958-1669(93)90059-6

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  3 in total

1.  Construction, expression and characterization of chimaeric toxins containing the ribonucleolytic toxin restrictocin: intracellular mechanism of action.

Authors:  D Rathore; J K Batra
Journal:  Biochem J       Date:  1997-06-15       Impact factor: 3.857

2.  Hybrid proteins between Pseudomonas aeruginosa exotoxin A and poliovirus 2Apro cleave p220 in HeLa cells.

Authors:  I Novoa; M Cotten; L Carrasco
Journal:  J Virol       Date:  1996-05       Impact factor: 6.549

3.  Targeted photodestruction of human colon cancer cells using charged 17.1A chlorin e6 immunoconjugates.

Authors:  M Del Governatore; M R Hamblin; E E Piccinini; G Ugolini; T Hasan
Journal:  Br J Cancer       Date:  2000-01       Impact factor: 7.640

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.